|This issue is sponsored by:|
|1. Editor's Message
Carl Wonders, PhD
ISSCR 12th Annual Meeting, June 18-21, 2014, Vancouver, Canada. Abstract submission and registration open Thursday, December 12! Plan to join us in the beautiful city of Vancouver this June and learn about the latest developments while adding your own discoveries to the conversation. Read more in Section 2.
ISSCR Connect. Join us tomorrow, December 11, at 10 am ET (USA) as Dr. Jürgen Knoblich presents his talk entitled, "Modeling Early Human Brain Development in 3D Culture." See Section 3 for more programming information.
4th International Conference on Stem Cell Engineering, March 16-19, 2014, Coronado, California, USA. Co-presented by the Society for Biological Engineering and the ISSCR. This meeting brings together biologists, engineers and clinicians who are working on cellular therapies to accelerate progress in designing the stem cell and its environment. Abstract submission is open through December 20, 2013. Read more.
Congratulations to Sabine Middendorp, Utrecht, the Netherlands, winner of the Membership Survey drawing! Dr. Middendorp's name was selected from those who participated in the ISSCR Membership Survey, and she will receive complimentary registration to a 2014 ISSCR meeting of her choice.
2014 ISSCR Dues. Members like you create the ISSCR community that serves as the globally respected voice for the field of stem cell research. Our improved online dues renewal system makes it easier than ever to stay connected to the people and resources that support your professional growth. Renew your membership today and continue to receive full benefits, including eligibility for ISSCR travel awards, access to educational content on ISSCR Connect and discounted registration rates.
Join the ISSCR and be a part of a global community. The ISSCR community that serves as the globally respected voice in the field of stem cell research. Our improved, online membership application makes it easier than ever to connect with people and resources that can support your professional growth. Join today to receive full member benefits, including eligibility for ISSCR travel awards, access to educational content on ISSCR Connect and discounted registration rates.
Sponsor The Pulse and Get Noticed. Promote your products and services to more than 14,000 members of the stem cell community by being an exclusive sponsor of The Pulse. Openings for 2014 issues are available. For information about sponsorship, contact Amy Claver.
|2. ISSCR 12th Annual Meeting
ISSCR 12th Annual Meeting
June 18-21, 2014
Vancouver, British Columbia, Canada
Co-sponsored by STEMCELL Technologies
Registration and abstract submission open Thursday, December 12!
Learn about the latest discoveries across the breadth of stem cell research by registering for the ISSCR 12th Annual Meeting. Learn more about the scientific program, confirmed speakers and traveling to Vancouver on the Annual Meeting website. Register before February 28, 2014, to receive the best rates. Not yet an ISSCR member? Join today and save even more.
Share your own research by submitting an abstract. Concurrent speaking slots as well as poster and travel awards are selected from the abstracts we receive. Read the Call for Abstracts for more information. The deadline for submitting an abstract is February 11, 2014.
Discover additional topics and perspectives in stem cell science by participating in our Wednesday morning events, including the Industry Wednesday Symposia and Focus Sessions, and Meet-up Hubs.
Travel Awards are available. When submitting your abstract, apply to be considered for a travel award. These awards will cover the cost of your registration and include a stipend to help defray the costs of traveling to Vancouver.
Poster Awards. Trainee members can also elect to be considered for a Poster Award when submitting their abstract. The six 2013 winners received complimentary registration to the 2014 Annual Meeting, a one-year subscription to Cell Stem Cell and Current Protocols in Stem Cell Biology and a cash stipend. In addition, each was given the opportunity to present their poster as a 10-minute talk on ISSCR Connect, which was made available to all registrants of the 2013 Annual Meeting last August.
Special Interest Group Meet-Ups. Several hubs have been set aside on the exhibition hall floor to provide informal meeting areas for groups interested in discussing research and related topics of mutual interest. If you are interested in developing and moderating such a session, contact Carl Wonders.
Plan to arrive early! Each year, the ISSCR offers Focus Sessions and Industry Wednesday Symposia the morning before the start of the Annual Meeting. These sessions provide opportunities for members, non-profit organizations and companies to extend the range of topics covered by the meeting.
- Focus Sessions are member-organized presentations that offer parallel, in-depth educational opportunities and explore unique issues relating to stem cell research. To date, two Focus Sessions are being organized:
Ethics, Stem Cells and the Information Age – presented by the ISSCR Ethics and Public Policy Committee
Engaging the Engine - How Public/Private Partnerships Between Academia and Industry Can Facilitate More Efficient Translation – presented by the ISSCR Industry and Junior Investigator Committees.
If you are interested in proposing a Focus Session to add to the 2014 pre-meeting program, download the Request for Proposals.
- Industry Wednesday Symposia sessions give companies the opportunity to present topical scientific issues in stem cell science as framed by industry leaders. If your company is interested in participating or would like more information, contact Amy Claver or Drew Rich today!
Help spread the word! Download the ISSCR 12th Annual Meeting PowerPoint® slide for use in your next presentation.
Visit our co-sponsor, STEMCELL Technologies.
|3. ISSCR Connect
ISSCR Connect is an online, educational and interactive portal that provides learning opportunities and the ability to make connections and open new avenues of communication in our fast-moving field throughout the year.
Our programming lineup for December and January includes our monthly What's New at the ISSCR news update, the final two talks in our neural stem cell series given by Jürgen Knoblich and Fred H. Gage and the last talk in our series featuring previous winners of the ISSCR Outstanding Young Investigator Award given by Joanna Wysocka.
Available to all, the ISSCR Connect Public Channel features news and other general information about stem cells and the ISSCR. If you are not a member of the ISSCR and would like an account on ISSCR Connect, fill out our online registration form .
What's New at the ISSCR – Broadcasting monthly, "What's New at the ISSCR" discusses the latest developments within the ISSCR. Hear about new ISSCR programs, bring your questions and participate using the live chat and Q&A features!
The program begins at 10 am ET (USA). Calculate your local time
Can't make it? The program will be available on-demand after the broadcast
As an ISSCR member benefit, the ISSCR Connect Members Channel provides additional educational opportunities through scientific presentations and other programming. All ISSCR members automatically receive an ISSCR Connect account with access to the Members and Public Channels.
||Jürgen Knoblich, PhD, will present on December 11 at 10 am ET (USA), and the title of his talk will be "Modeling Early Human Brain Development in 3D Culture." Click here to be taken to the presentation page, where you can add the event to your calendar.
||The final talk in our neural stem cell series will be given by Fred H. Gage, PhD on January 7 at 3 pm ET (USA).
||Joanna Wysocka, PhD will present the concluding talk in our series featuring previous OYIA winners. Her talk, entitled "Stem Cells, Enhancers and the Emergence of Epigenomes in Development" will be given on January 22 at 2 pm ET (USA).
Coming in 2014: in the early months of 2014, we will be beginning two new series focusing on Stem Cells and Cancer and Building Organs with Stem Cells. Speaker information will be available on the the ISSCR website and on ISSCR Connect once it is finalized.
|4. News Roundup
Italy. On December 4, a regional court found that the scientific committee that had advised the Italian health minister against proceeding with a clinical trial of a stem cell-based therapy developed by the Stamina Foundation was ruled unlawful, reopening the possibility for government sponsorship. Read more.
Italy. A petition signed by 13,000 scientists in protest of a law passed in July that places heavy restrictions on the use of animals in research was delivered to the Italian Chamber of Deputies on December 5. The law still must be signed by the Italian president to take effect. Read more.
Japan. On December 5, the Kyoto University Center for iPS Cell Research and Application announced the creation of a stockpile of iPSCs for future use in regenerative medicine and clinical research. Read more.
Washington, DC, USA. The National Human Neural Stem Cell Resource (NHNSCR) announced the creation of an iPSC repository containing lines derived from patient with idiopathic autism and FMR1 gene mutations. Read more on the NHNSCR website.
|5. Job Opportunities
Seeking a job? Have a job opening? Visit the ISSCR’s Job Bank. ISSCR members receive a discount on job postings.
Featured Job Posting. Now you can feature your job opening both on the ISSCR Job Bank and in the ISSCR’s monthly e-newsletter, The Pulse. Our e-newsletter is sent to more than 14,000 professionals in the stem cell field, so take advantage of this additional exposure!
|7. Meetings and Courses
ISSCR Meetings and Events
4th International Conference on Stem Cell Engineering
Regional Forum Series 2014
Co-presented by the Society for Biological Engineering and the ISSCR
March 16 - 19, 2014
Coronado, California, USA
Abstract Submission Deadline: December 20, 2013
ISSCR 12th Annual Meeting
Co-Sponsored by STEMCELL Technologies
June 18 - 21, 2014
Global Controls in Stem Cells
Regional Forum Series 2014
Co-organized by ISSCR and Stem Cell Society Singapore
November 5-7, 2014
Stem Cell Meetings
The 7th Takeda Science Foundation Symposium on PharmaSciences
January 16 - 18, 2014
Associated with the CiRA International Symposium 2014
Keystone Symposia: Stem Cells and Cancer
February 2 - 7, 2014
Banff, Alberta, Canada
Discounted Registration Deadline: February 2, 2014
CHI's Targeting Cancer Stem Cells: New Opportunities for Oncology Therapeutics
February 13 - 14, 2014
San Francisco, CA, USA
Discounted Registration Deadline: January 10, 2014
February 17 - 19, 2014
London, United Kingdom
Keystone Symposia: Stem Cells and Reprogramming
April 6 - 11, 2014
Olympic Valley, California
Scholarship Application Deadline: December 10, 2013
Abstract Submission Deadline: January 15, 2014
Discounted Registration Deadline: February 6, 2014
Registration Closes: April 6, 2014
Keystone Symposia: Adult Neurogenesis
May 12 - 17, 2014
Scholarship Application Deadline: January 13, 2014
Abstract Submission Deadline: January 13, 2014
Late Abstract Submission Deadline: February 13, 2014
Discounted Registration Deadline: March 12, 2014
May 29 - 30, 2014
New York, NY USA
Registration Opens: January 2014
Abstract Submission Deadline: March 7, 2014
Upcoming Stem Cell Courses
Human ES/iPS Cell Research
March 25 - 28, 2014
MACS Academy, Miltenyi Biotec
Bergisch Gladbach/Cologne, Germany
View a list of recurring courses and seminar/meeting series.
|8. Literature Highlights
Stem Cell Reports
The November 19 issue of the ISSCR's online, open-access journal, Stem Cell Reports, is now available. Read about the highlights from this issue here and visit the Stem Cell Reports website or click the citations below to read each individual paper.
New articles are available every week online, and the December issue is just around the corner!
About the cover. This month's cover shows wild type and CCR4 deadenylase-mutant Drosophila ovarioles stained for DAPI, anti-Vasa, a germ cell marker, and 1B1 to label germ stem cells.
Read the complete table of contents.
Nielen, M.G., de Vries, S.A., and Geijsen, N. (2013). European stem cell research in legal shackles. EMBO J doi:10.1038/emboj.2013.249.
Lysaght, T., Kerridge, I., Sipp, D., Porter, G., and Capps, B.J. (2013). Oversight for clinical uses of autologous adult stem cells: lessons from international regulations. Cell Stem Cell 13, 647–651.
Brennand, K.J. (2013). Inducing cellular aging: enabling neurodegeneration-in-a-dish. Cell Stem Cell 13, 635–636.
Refers to Miller et al., 2013.
Chu, S.H. and Armstrong, S.A. (2013). Stem Cells: Dual Response to Ras Mutation. Nature 504, 91-92.
Refers to Li et al., 2013.
Dutta, D., Xiang, J. and Edgar, B. A. (2013). RNA Expression Profiling from FACS-Isolated Cells of the Drosophila Intestine. Curr Protoc Stem Cell Biol 27:2F.2.1–2F.2.12.
Mirsaidi, A., Tiaden, A. N. and Richards, P. J. (2013). Preparation and Osteogenic Differentiation of Scaffold-Free Mouse Adipose-Derived Stromal Cell Microtissue Spheroids (ASC-MT). Curr Protoc Stem Cell Biol 27:2B.5.1–2B.5.12
Aprea, J., Prenninger, S., Dori, M., Ghosh, T., Monasor, L.S., Wessendorf, E., Zocher, S., Massalini, S., Alexopoulou, D., Lesche, M., et al. (2013). Transcriptome Sequencing During Mouse Brain Development Identifies Long Non-Coding RNAs Functionally Involved In Neurogenic Commitment. EMBO J. doi:10.1038/emboj.2013.245
Bellin, M., Casini, S., Davis, R.P., D'Aniello, C., Haas, J., Ward-van Oostwaard, D., Tertoolen, L.G.J., Jung, C.B., Elliott, D.A., Welling, A., et al. (2013). Isogenic Human Pluripotent Stem Cell Pairs Reveal The Role Of A KCNH2 Mutation In Long-QT Syndrome. EMBO J. doi:10.1038/emboj.2013.240
Chan, Y.-S., Göke, J., Ng, J.-H., Lu, X., Gonzales, K.A.U., Tan, C.-P., Tng, W.-Q., Hong, Z.-Z., Lim, Y.-S., and Ng, H.-H. (2013). Induction of a human pluripotent state with distinct regulatory circuitry that resembles preimplantation epiblast. Cell Stem Cell 13, 663–675.
Hirose, S., Takeyama, N., Nakamura, S., Nagasawa, K., Ochi, K., Hirata, S., Yamazaki, S., Yamaguchi, T., Otsu, M., Sano, S., Takahashi, N., Sawaguchi, A., Ito, M., Kato, T., Nakauchi, H. and Eto, K. (2013). Immortalization of Erythoroblasts by c-MYC and BCL-XL Enables Large-scale Erythrocyte Production From Human Pluripotent Stem Cells. Stem Cell Reports doi:10.1016/j.stemcr.2013.10.010
Li, Q., Bohin, N., Wen, T., Ng, V., Magee, J., Chen, S.-C., Shannon, K., and Morrison, S.J. (2013). Oncogenic Nras Has Bimodal Effects On Stem Cells That Sustainably Increase Competitiveness. Nature 504, 143–147.
Marchetto, M.C.N., Narvaiza, I., Denli, A.M., Benner, C., Lazzarini, T.A., Nathanson, J.L., Paquola, A.C.M., Desai, K.N., Herai, R.H., Weitzman, M.D., Yeo, G.W., Muotri, A.R. and Gage, F.H.. (2013). Differential L1 Regulation In Pluripotent Stem Cells of Humans and Apes. Nature 503, 525–529.
Mertens, J., Stüber, K., Wunderlich, P., Ladewig, J., Kasavan, J.C., Vandenberghe, R., Vandenbulcke, M., van Damme, P., Walter, J., Brüstle, O. and Koch, P. (2013). APP Processing in Human Pluripotent Stem Cell-derived Neurons Is Resistant to NSAID-Based -Secretase Modulation. Stem Cell Reports doi:10.1016/j.stemcr.2013.10.011.
Miller, J.D., Ganat, Y.M., Kishinevsky, S., Bowman, R.L., Liu, B., Tu, E.Y., Mandal, P.K., Vera, E., Shim, J.-W., Kriks, S., et al. (2013). Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging. Cell Stem Cell 13, 691–705.
Singh, A.M., Chappell, J., Trost, R., Lin, L., Wang, T., Tang, J., Wu, H., Zhao, S., Jin, P. and Dalton, S. (2013). Cell-cycle Control of Developmentally Regulated Transcription Factors Accounts for Heterogeneity in Human Pluripotent Cells. Stem Cell Reports doi:10.1016/j.stemcr.2013.10.009.
Wang, L., Miao, Y.-L., Zheng, X., Lackford, B., Zhou, B., Han, L., Yao, C., Ward, J.M., Burkholder, A., Lipchina, I., et al. (2013). The THO Complex Regulates Pluripotency Gene mRNA Export and Controls Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming. Cell Stem Cell 13, 676–690.