|This issue is sponsored by:|
|1. Editor's Message
Carl Wonders, PhD
ISSCR 12th Annual Meeting: June 18-21, 2014, Vancouver, Canada. Co-sponsored by STEMCELL Technologies. The ISSCR will return to Canada for the ISSCR 11th Annual Meeting. Abstract submission and registration open December 12, 2013. Read more in Section 2.
ISSCR Connect. October features a host of new programming, including a Neural Stem Cell series, talks from ISSCR Outstanding Young Investigators and content from the ISSCR’s Stem Cells in Translation meeting from September in Florence Italy. Read more about our upcoming programming in Section 3.
4th International Conference on Stem Cell Engineering. Co-presented by the Society for Biological Engineering (SBE) and the ISSCR. This meeting brings together biologists, engineers and clinicians who are working on cellular therapies to accelerate progress towards designing the stem cell and its environment. Abstract submission is now open through December 10, 2013. Learn more.
|Reminder: ISSCR Membership Survey. We want your feedback! The 2013 Membership Survey was emailed on September 30, and we thank everyone who has already replied. If you’ve not yet submitted your responses, there is still time to do so. You will also have the option to be entered into a drawing to win a free registration to an ISSCR meeting of your choice.
|We're making it even easier to become a member of the ISSCR. This November, we will be unveiling our new online membership application. This user-friendly system will streamline the application process, making it even simpler to apply and be endorsed for membership.
ISSCR Awards Nominations. Each year, the ISSCR honors innovative work done to harness the potential of stem cells and celebrates the achievements of an exceptional early career investigator. Nominations are now open for the following awards:
- The McEwen Award for Innovation, supported by the McEwen Centre for Regenerative Medicine in Toronto, Canada, recognizes original thinking and ground-breaking research pertaining to stem cells or regenerative medicine that opens new avenues of exploration towards the understanding or treatment of human disease or affliction.
- The ISSCR Outstanding Young Investigator Award recognizes the exceptional achievements of an investigator in the early part of his or her independent career in stem cell research.
Nominations for both awards will be accepted through October 23, 2013. For more information, to view past winners or to submit your nominations, visit the ISSCR Awards webpage or email Glori Rosenson.
ISSCR Board of Directors Nominations. The ISSCR is soliciting nominations for international representatives to the board of directors with terms beginning June 2014. New board members will be elected to a three-year term and are eligible for an additional one-term appointment. Board members are expected to attend two board meetings per year (one held in conjunction with the ISSCR Annual Meeting), actively participate in the ISSCR Annual Meeting and other events and assume volunteer leadership positions within the society.
Nominations can be made by all current ISSCR members in good standing and should include the nominee’s contact information. All eligible candidates will be reviewed by the ISSCR Nominating Committee for possible inclusion in the slate for the general membership election that will begin in February 2014. Email your nominations to ISSCR Executive Director/CEO Nancy Witty by midnight (CST), November 1, 2013.
Sponsor The Pulse and Get Noticed. Promote your products and services to more than 14,000 members of the stem cell community by being an exclusive sponsor of The Pulse. Openings for 2014 issues are available. For information about sponsorship, contact Amy Claver.
|2. ISSCR 12th Annual Meeting
ISSCR 12th Annual Meeting
June 18-21, 2014
Co-sponsored by STEMCELL Technologies
In 2014, we will return to Canada, as the beautiful city of Vancouver, British Columbia will host the ISSCR 12th Annual Meeting.
The ISSCR 12th Annual Meeting website has been updated and now includes a preliminary schedule of the meeting.
Read the latest information on the plenary and concurrent topics.
View the list of confirmed speakers.
Abstract submission and registration for this meeting will open December 12, 2013.
Travel awards are available. Apply when submitting your abstract to be considered to receive a travel award. These awards will cover the cost of your registration to the meeting and include a stipend to help defray the costs of traveling to Vancouver.
Help spread the word! Download the ISSCR 12th Annual Meeting PowerPoint® slide for use at the end of your next presentation.
Visit our co-sponsor, STEMCELL Technologies
|3. ISSCR Connect
ISSCR Connect is an online, educational and interactive portal that provides learning opportunities and the ability to make connections and open new avenues of communication in our fast-moving field throughout the year.
Don’t miss October’s blockbuster lineup: Sebastian Jessberger kicks off a new series focused on neural stem cells; Cédric Blanpain, the ISSCR’s 2012 Oustanding Young Investigator, has his presentation available on-demand through the 21st; and enjoy highlights from ISSCR’s Stem Cells in Translation Regional Forum in Florence starting tomorrow. Read on for details.
Did you attend the ISSCR’s Stem Cells in Translation Regional Forum in Florence? We are pleased to offer free access to the ISSCR Connect Members Channel for October and November. You will receive an email on Wednesday with your login and password. Contact Carl Wonders with any questions or if you have trouble logging in.
Available to all, the ISSCR Connect Public Channel features news and other general information about stem cells and the ISSCR. If you are not a member of the ISSCR and would like an account on ISSCR Connect, fill out our online registration form .
What's New at the ISSCR – Broadcasting monthly every second Wednesday of the month, "What's New at the ISSCR" is monthly program discussing the latest developments within the ISSCR. Hear about new ISSCR programs, bring your questions and participate using the live chat and Q&A features!
The program begins at 10 am ET (USA). Calculate your local time
Can't make it? The program will be available on-demand after the broadcast
As an ISSCR member benefit, the ISSCR Connect Members Channel provides additional educational opportunities through scientific presentations and other programming. All ISSCR members automatically receive an ISSCR Connect account with access to the Members and Public Channels.
|Having trouble accessing your account? Email Carl Wonders for assistance.
|Not yet a member? Join today and gain access to this additional content.
||If you missed yesterday's presentation by Cédric Blanpain, the 2012 recipient of the ISSCR Outstanding Young Investigator Award, his talk is available on -demand to all ISSCR members through Monday, October 21. Click here to access this presentation (login required).
||Highlights from September’s Stem Cells in Translation Regional Forum in Florence, Italy. The first group of presentations will be made available on-demand starting Wednesday, October 9 to all ISSCR members and all meeting registrants. Whether you were unable to make it to Florence or would like to revisit a talk you saw there, be sure to take advantage of this opportunity! Click here to see the schedule of talks.
||Sebastian Jessberger, MD, PhD will present the first talk in a series focusing on neural stem cells. His presentation, entitled “Molecular and Cellular Mechanisms Regulating Adult Neurogenesis” will begin at 10 am Eastern Time (USA) on October 24, 2013. Calculate your local time or click on the title above to be taken directly to the presentation page in ISSCR Connect.
|4. News Roundup
California, USA. On October 1, 2013, Asterias Biotherapeutics, Inc., a subsidiary of BioTime, Inc. announced that it had acquired the embryonic stem cell assets previously held by Geron Corp. Read the news release.
California, USA. On October 2, 2013, the US Food and Drug Administration (FDA) announced the authorization of StemCells Inc.’s application for the testing of its proprietary human neural stem cells as a treatment for spinal cord injury in a phase I/II clinical trial. Read the news release .
Sweden. The Karolinska Institute announced that James E. Rothman, Randy W. Schekman and Thomas C. Südhof were the co-recipients of the 2013 Nobel Prize for Physiology or Medicine on October 7. Their work was key to our understanding of how cells transport and release proteins, a process that is implicated in a variety of cellular processes and diseases. Read more.
|5. Job Opportunities
Seeking a job? Have a job opening? Visit the ISSCR’s Job Bank. ISSCR members receive a discount on job postings.
Featured Job Posting. Now you can feature your job opening both on the ISSCR Job Bank and in the ISSCR’s monthly e-newsletter, The Pulse. The e-newsletter is sent to more than 14,000 professionals in the stem cell field, so take advantage of this additional exposure!
|7. Meetings and Courses
Stem Cells in Science and Medicine
ISSCR 2013 Regional Forum Series
Co-Sponsored by ISSCR and Cold Spring Harbor Asia
October 14 - 17, 2013
Stem Cell Meetings
Quantitative Single Cell Biology in Stem Cell Research
October 10 - 11, 2013
Ludwig Maximilians University
Stem Cell Meeting on the Mesa
October 14 - 16, 2013
La Jolla, CA, USA
Housing Discount Deadline: September 26, 2013
The New York Stem Cell Foundation Research Institute's Eighth Annual Translational Stem Cell Research Conference
October 16 - 17, 2013
Caspary Auditorium, The Rockefeller University
New York, NY, USA
Discounted Registration Deadline: September 14, 2013
2013 Shanghai International Symposium on Cancer Stem Cells
October 17 - 19, 2013
Tongji University, Shanghai, China
World Conference on Regenerative Medicine 2013
October 23 - 25, 2013
Regenerative Medicine: from Biology to Therapy
October 30 - November 1, 2013
Wellcome Trust Conference Centre
Hinxton, Cambridge, UK
Abstract Submission Deadline: September 13, 2013
Registration Closes: October 2, 2013
TERMIS-AM 2013 Conference & Expo
November 10 - 13, 2013
Hyatt Regency Atlanta
Atlanta, Georgia, USA
Discounted Registration Deadline: September 15, 2013
First Annual Conference 2013 of the German Stem Cell Network (GSCN)
November 11 - 13, 2013
Abstract Submission Deadline: September 30, 2013
Discounted Registration Deadline: September 30, 2013
Registration Closes: October 31, 2013
Stem Cell Society Singapore Symposium 2013
November 18-19, 2013
Poster Abstract Deadline: October 1, 2013
Online Registration Closes: November 4, 2013
3rd World Congress on Cell Science & Stem Cell Research
November 20 - 22, 2013
Baltimore, MD, USA
Cell Symposia: Using Stem Cells to Model and Treat Human Disease
November 21-23, 2013
Los Angeles, California, USA
Innovating the Marketplace with Stem Cells
November 29, 2013
Convention Centre, Darling Harbour
Early Registration Discount: October 24, 2013
The 6th Annual Maryland Stem Cell Research Symposium
December 3, 2013
Johns Hopkins Medical Campus
Baltimore, MD, USA
Abstract Submission Deadline: October 8, 2013
2013 World Stem Cell Summit
December 4 - 6, 2013
San Diego, CA USA
Abstract Submission Deadline: October 29, 2013
Discounted Registration Deadline: October 29, 2013
Hotel Discount Deadline: November 8, 2013
Annual Symposium - Biochemical Determinants of Tissue Regeneration
December 11 - 13, 2013
Shrigley Hall Hotel
Abstract Submission Deadline: October 9, 2013
Discounted Registration Deadline: November 11, 2013
2013 American Society for Cell Biology Annual Meeting
December 14 - 18, 2013
New Orleans, LA USA
Upcoming Stem Cell Courses
Current Protocols Webinar:
Stem Cell and Reprogramming Research Methods: Practical Considerations for Studies of Disease Including Culture Methods and Genetic Manipulation.
October 10, 2013
12:00 – 1:00 pm ET (USA)
Induced Pluripotent Stem (iPS) Cell Training Workshop
October 30 - November 1, 2013
AIBN, University of Queensland
Registration Closes: October 20, 2013
View the complete list of upcoming and recurring courses.
|9. Literature Highlights
Jaglin, X. H. and Fishell,G. (2013). A foot in the door: how the chromatin modifier Brg1 and Pax6 jointly potentiate adult neurogenesis. Cell Stem Cell 13, 373-374.
Refers to Ninkovic et al., 2013.
Livyatan, I. and Meshorer, E. (2013). SON sheds light on RNA splicing and pluripotency. Nat Cell Biol 15, 1139-1130.
Refers to Lu et al., 2013.
Bell, G. I., Seneviratne, A. K., Nasri, G. N. and Hess, D. A. (2013). Transplantation models to characterize the mechanisms of stem cell–induced islet regeneration. Curr Protoc Stem Cell Biol 26:2B.4.1–2B.4.35.
Luo, Y., Nguyen, N. and Fujita, M. (2013). Isolation of human melanoma stem cells using ALDH as a marker. Curr Protoc Stem Cell Biol 26:3.8.1–3.8.10.
Mallanna, S. K. and Duncan, S. A. (2013). Differentiation of hepatocytes from pluripotent stem cells. Curr Protoc Stem Cell Biol 26:1G.4.1–1G.4.13.
Weinger, J. G., Chen, L., Coleman, R., Leang, R., Plaisted, W. C., Loring, J. F. and Lane, T. E. (2013). Intraspinal transplantation of mouse and human neural precursor cells. Curr Protoc Stem Cell Biol 26:2D.16.1–2D.16.16.
Bernardo, M. E. and Fibbe, W. E. (2013). Mesenchymal stromal cells: sensors and switches of inflammation. Cell Stem Cell 13, 392-402.
Ugarte, F. and Forsberg, E. C. (2013). Haematopoietic stem cell niches: new insights inspire new questions. EMBO J 32, 2535-2547.
Gancz, D. and Gilboa, L. (2013). Insulin and target of rapamycin signaling orchestrate the development of ovarian niche-stem cell units in Drosophila. Development 140, 4145-4154
Guo, G., Luc, S., Marco, E., Lin, T. W., Peng, C., Karenyi, M. A., Beyaz, S., Kim, W., Xu, J., Das, P. P., Neff, T., Zou, K., Yuan, G. C. and Orkin, S. H. (2013). Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire. Cell Stem Cell 13, 492-505.
Huch, M., Bonfanti, P., Boj, S. F., Sato, T., Loomans, C. J. M., van de Wetering, M., Sojoodi, M., Li, V. S. W., Schuijers, J., Gracanin, A., Ringnalda, F., Begthel, H., Hamer, K., Mulder, J., van Es, J. H., de Koning, E., Vries, R. G. J., Heimberg, H. and Clevers, H. (2013). Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis. EMBO J doi:10.1038/emboj.2013.204.
Lu, X., Göke, J., Sachs, F., Jacques, P. E., Liang, H., Feng, B., Bourque, G., Babulya, P. A. and Ng, H. H. (2013). SON connects the splicing-regulatory network with pluripotency in human embryonic stem cells. Nat Cell Biol 15, 1141-1152.
Martello, G., Bertone,P. and Smith, A. (2013). Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor. EMBO J 32, 2561-2574.
Ninkovic, J., Steiner-Mezzadri, A., Jawerka, M., Akinci, U., Masserdotti, G., Petricca, S., Fischer, J., von Holst, A., Beckers, J., Lie, C. D., Petrik, D., Miller, E., Tang, J., Wu, J., Lefebvre, V., Demers, J., Eisch, A., Metzger, D., Crabtree, G., Irmler, M., Poot, R. and Götz, M. (2013). The BAF comples interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network. Cell Stem Cell 13, 403-418.
Niu W., Zang, T., Zou, Y., Fang, S., Smith, D. K., Bachoo, R. and Zhang, C. L. (2013). In vivo reprogramming of astrocytes to neuroblasts in the adult brain. Nat Cell Biol 15, 1164-1175.
Rizzoti, K., Akiyama, H. and Lovell-Badge, R. (2013). Mobilized adult pituitary stem cells contribute to endocrine regeneration in response to physiological demand. Cell Stem Cell 13, 419-432.
Soyombo, A. A., Wu, Y., Kolski, L., Rios, J. J., Rakheja, D., Chen, A., Kehler, J., Hampel, H., Coughran, A. and Ross, T. S. (2013). Analysis of induced pluripotent stem cells from a BRCA1 mutant family. Stem Cell Reports doi:10.1016/j.stemcr.2013.08.004.
Takayama, K., Naamoto, Y., Mimura, N., Tashiro, K., Sakurai, F., Tachibana, M., Hayakawa, T., Kawabata, K. and Mizuguchi, H. (2013). Long-term self-renewal of human ES/iPS-derived hepatoblast-like cells on human laminin 111-coated dishes. Stem Cell Reports doi:10.1016/j.stemcr.2013.08.006.