|This issue is sponsored by:|
|1. Editor's Message
Carl Wonders, PhD
ISSCR Regional Forum Series 2013. This year in addition to our Annual Meeting, the ISSCR is introducing two Regional Forums as part of the ISSCR Regional Forum Series 2013. Designed to complement the Annual Meeting, Regional Forums provide additional opportunities to hear the latest findings and breakthroughs in stem cell research in your part of the world in a relaxed and participatory environment.
Registration is open for both of these events. Click on the above links for more information.
ISSCR 2014: Save the Date. The ISSCR 12th Annual Meeting, co-sponsored by STEMCELL Technologies will be held in Vancouver, Canada, June 18-21, 2014. Abstract Submission and Registration will open in December. Visit the annual meeting website for more information. See the list of featured speakers.
ISSCR Connect.Thank you to all who participated in and viewed the content from the ISSCR 11th Annual Meeting. Beginning this month, we will be rolling out new programs and content. Check Section 4 for more information.
Stem Cell Reports. The second issue of the ISSCR's online, open-access journal, Stem Cell Reports, is now available. All issues are freely available. Visit the Stem Cell Reports webpage for more information and see Section 9 for a complete table of contents.
Sponsor The Pulse and Get Noticed. Promote your products and services to more than 14,000 members of the stem cell community by being an exclusive sponsor of The Pulse. Openings for 2014 issues are available. For more information about sponsorship, contact Amy Claver.
|2. Florence 2013 Regional Forum
Stem Cells in Translation
September 15-18, 2013
|Late Abstract Submission Deadline
|Advance Registration Deadline
The ISSCR invites you to Florence, Italy for Stem Cells in Translation, September 15-18, 2013. The goal of this Regional Firum is to foster collaboration and facilitate discussion among the field’s leading researchers about what is needed to translate stem cell research into cell and gene therapies. Learn more about the meeting, the science and the location on the Florence 2013 website.
It’s not too late to submit an abstract! Late abstract submissions are being accepted until August 23. Late abstracts should be submitted to email@example.com. Please note that late abstracts will not be printed in the final program. Read more about submitting a late abstract.
IMPORTANT: If you have submitted an abstract but have not yet registered for the meeting, please do so by Thursday, August 15 at 5 p.m. Central Daylight Time (USA) to ensure your abstract is included in the final program. Note: if you are unable to register by Thursday but plan to do so, please make arrangements by contacting ISSCR Headquarters.
Register online and save off of the on-site rate. ISSCR members enjoy additional savings; if you’re not yet a member, join today and receive the member rate immediately.
|3. Suzhou 2013 Regional Forum
Stem Cells in Science and Medicine
Co-organized by Cold Spring Harbor Asia
October 14 - 17, 2013
The Abstract Submission Deadline has been extended to August 16. Registration and Abstract submission for this meeting are available through the Cold Spring Harbor Asia website. Please note that you must register for the meeting first if you wish to submit an abstract – you will be given a link and instructions for abstract submission in your registration confirmation email.
The ISSCR is pleased to return to Suzhou and once again partner with Cold Spring Harbor Asia to present Stem Cells in Science and Medicine. The diverse program offers a wide range of stem cell topics including Stem Cells & Development, iPS and Reprogramming, Cancer Stem Cells and Therapy and more. View the complete list of sessions and confirmed speakers.
More details, including hotel and travel information, can be found on the Stem Cells in Science and Medicine website.
|4. ISSCR Connect
ISSCR Connect is our online platform for delivering educational content. Containing three channels: Public, Members and Events, ISSCR Connect provides news, science and other stem cell content live and on-demand.
Thank you to the presenters from the ISSCR 11th Annual Meeting who agreed to have their content hosted on ISSCR Connect . Your participation benefited more than 1,000 viewers and added considerable value for the meeting registrants.
Available to all, the ISSCR Connect Public Channel features news and other general information about stem cells and the ISSCR. If you are not a member of the ISSCR and would like an account on ISSCR Connect, fill out our online registration form .
What's New at the ISSCR – Resuming this August 20, "What's New at the ISSCR" is monthly program discussing the latest developments within the ISSCR. Hear about new ISSCR programs, bring your questions and participate using the live chat and Q&A features!
The program begins at 10 am ET (USA). Calculate your local time
Can't make it? The program will be available on-demand after the broadcast
An ISSCR member benefit, the ISSCR Connect Members Channel provides additional educational opportunites through scientific presentations and other programming. All ISSCR members automatically receive an ISSCR Connect account with access to the Members and Public Channels. Not yet a member? Join today and gain access to this additional content.
Outstanding Young Investigator Award Winner Spotlight Series
Beginning August 27, we will be featuring the previous winners of the ISSCR-University of Pittsburgh Outstanding Young Investigator Award.
We will rebroadcast the OYIA lecture from Marius Wernig, MD, PhD, Stanford University, from the ISSCR 11th Annual Meeting in Boston You will have two opportunities to view this presentation.
Dr. Werning's talk will be available at the following times. Please note: this presentation will not be made available on demand.
11 a.m. EDT (USA): Calculate your local time.
11 p.m. EDT (USA): Calculate your local time.
Dr. Wernig's talk will also be available for viewing at these times on the Events Channel for registrants of the annual meeting.
Robert Blelloch, MD, PhD, University of California, San Francisco, who is the 2011 recipient of the Outstanding Young Investigator Award, will present the second lecture in this series.
Dr. Blelloch will present live on Monday, September 23 at 4 PM EDT (USA). Calculate your local time.
Cédric Blanpain, MD, PhD, Université Libre de Bruxelles, Belgium, received the Outstanding Young Investigator Award in 2012 and will present the third lecture in this series this October. Stay tuned for the specific date and time in the near future.
||Joanna Wysocka, PhD, Stanford School of Medicine, was the second recipient of the Outstanding Young Investigator Award in 2010.
Coming this Fall: Spotlight on Neural Stem Cells
In the coming months, we will be highlighting the field of neural stem cells through new, live presentations. Arnold Kreigstein, MD, PhD, University of California, San Francisco, will be presenting the latest research from his lab on November 20, and we are currently finalizing the schedule of content for talks in September and October, so check your inbox and the upcoming programs tab in the Members Channel for more information!
All registrants of the ISSCR 11th Annual Meeting currently have access to the Events Channel. On August 27, all annual meeting registrants will have two opportunities to view Marius Wernig's OYIA lecture (see the description in the Members Channel area above for more information). In addition to this presentation, three ISSCR Poster Award winners have been given the opportunities to present their winning research in the form of a talk. Take the time to watch these presentations, as they represent the work of future leaders in the stem cell community.
Having trouble logging in? Click here to reset your password. If you continue to have trouble, contact Carl Wonders for help.
|5. News Roundup
California, USA. On July 25, the California Institute for Regenerative Medicine (CIRM) approved a plan to create the Alpha Stem Cell Clinics Network, which will act as a hub for stem cell clinical trials. Read the press release. For more information about the Alpha Clinics concept, read the CIRM white paper
France. On July 17, the French Parliament passed a law allowing for embryonic and embryonic stem cell research, which replaces a partial ban that had been in place since 2004. Read more.
Italy. On July 31, the Italian Parliament approved a bill that would significantly limit the ability of scientists to use animals in their research. Read more.
|6. Job Opportunities
Seeking a job? Have a job opening? Visit the ISSCR Job Bank. ISSCR members receive a discount on job postings.
Featured Job: Two Principal Investigator positions in developmental and stem cell biology. The Developmental & Stem Cell Biology Program at The Hospital for Sick Children, Canada, invites applications for two PI positions with an academic appointment as an Assistant or Associate Professor at the University of Toronto. Read the full posting.
|8. Meetings and Courses
Stem Cell Meetings
MSC2013: Adult Stem Cell Therapy and Regenerative Medicine
August 19 - 21, 2013
Cleveland, OH USA
ISEH - 42nd Annual Scientific Meeting
Aug. 22 - 25, 2013
NHLBI Symposium on Cardiovascular Regenerative Medicine
September 25-26, 2013
National Institutes of Health
Bethesda, Maryland, USA
Quantitative Single Cell Biology in Stem Cell Research
October 10 - 11, 2013
Ludwig Maximilians University
2013 Shanghai International Symposium on Cancer Stem Cells
Oct. 17 - 19, 2013
Tongji University, Shanghai, China
World Conference on Regenerative Medicine 2013
Oct. 23 - 25, 2013
TERMIS-AM 2013 Conference & Expo
November 10 - 13, 2013
Hyatt Regency Atlanta
Atlanta, Georgia, USA
Discounted Registration Deadline: September 15, 2013
First Annual Conference 2013 of the German Stem Cell Network (GSCN)
November 11 - 13, 2013
Abstract Submission Deadline: September 30, 2013
Discounted Registration Deadline: September 30, 2013
Registration Closes: October 31, 2013
Stem Cell Society Singapore Symposium 2013
November 18-19, 2013
Early Registration Deadline: August 31, 2013
Oral Presentation Submission Deadline: September 1, 2013
Poster Abstract Deadline: October 1, 2013
Online Registration Closes: November 4, 2013
3rd World Congress on Cell Science & Stem Cell Research
November 20 - 22, 2013
Baltimore, MD, USA
Cell Symposia: Using Stem Cells to Model and Treat Human Disease
November 21-23, 2013
Los Angeles, California, USA
Early Registration Discount Deadline: August 30, 2013
2013 World Stem Cell Summit
December 4 - 6, 2013
San Diego, CA USA
Abstract Submission Deadline: October 29, 2013
Discounted Registration Deadline: October 29, 2013
Hotel Discount Deadline: November 8, 2013
2013 American Society for Cell Biology Annual Meeting
December 14 - 18, 2013
New Orleans, LA USA
Stem Cell Courses
EMBO Practical Course: Current methods in cell biology
Sept. 26 - Oct. 4, 2013
MACS Academy: Human ES/iPS Cell Research
November 5 - 8, 2013
Bergisch Gladbach/Cologne, Germany
Stem Cells: A Pathway Through the Maze
Dec. 11 - 13, 2013
Oxford, United Kingdom
Application Deadline: December 9, 2013
Regularly Occurring Courses
Cellular Dynamics International (CDI): iCertification Courses
Madison, WI, USA
Two-day training courses for CDI's iCell Products.
Life Technologies: LifeLab Pluripotent Stem Cell Workshops
Various Locations, Global
Training in culturing and characterizing hESCs and iPSCs and reprogramming techniques offered at various locations throughout the year.
STEMCELL Technologies: Training Courses
Vancouver, BC, Canada
Ongoing series of a range of specialized stem cell courses.
Courses and Seminar/Meeting Series
Cold Spring Harbor Laboratory Meetings and Courses
Cold Spring Harbor Laboratory
Cold Spring Harbor, NY, USA
European Molecular Biology Organisation (EMBO) Courses and Workshops
Held throughout Europe
European Science Foundation (ESF) Research Conferences
Held throughout Europe
EuroSciCon Life Science Meetings
(note: ask about ISSCR member discount)
FASEB Summer Resarch Conferences
Various locations in the USA
Scientific conferences for biological, chemical and physical sciences.
Marine Biological Laboratory (MBL) Courses and Programs
Woodshole, ME, USA
The Jackson Laboratory Courses, Meetings and Workshops
Bar Harbor, ME, USA
The Wellcome Trust Courses and Conferences
Cambridge, United Kingdom
Advanced laboratory-based courses at the Wellcome Trust Genome Campus or in association with international organizations
|9. Literature Highlights
Stem Cell Reports
||The August 6 issue of the ISSCR's online, open-access journal, Stem Cell Reports is now available. Read about the highlights from this issue here and visit the Stem Cell Reports website or click the citations below to read each individual paper.
Current Issue Highlights
The nature of very small embryonic-like cells (VSELs) has been debated since their reported discovery in 2006. Extracted from the bone marrow, VSELs have been described as a possible replacement for embryonic stem cells. However, in a report published by Miyanishi et al., their very existence has come into question.
About the cover: This month's cover features neurospheres grown from adult hippocampal neural stem/progenitor cells following infection with a tamoxifen-inducible Ascl1 retrovirus. In yellow are cells labeled with a neuronal marker (MAP2AB). The report, written by Braun et al., demonstrates the utility of inducible retroviruses in the transient control of gene expression in adult mouse neural progenitor cells.
|Read the paper
Miyanishi, M., Mori, Y., Seita, J., Chen, J. Y., Karten, S. Chan, C. K. F., Nakauchi, H. and Weissman, I. L. (2013). Do pluripotent stem cells exist in adult mice as very small embryonic stem cells? Stem Cell Reports 1, 198-208.
Abbot, A. (2013). Doubt cast over tiny stem cells. Nature 499, 390.
Cane S. (2013). A wild stem cell chase . The Scientist. Web. Accessed 13 August 2013.
Nicholls, H. (2013). VSELs: is ideology overtaking science? Cell Stem Cell 13, 143-144.
View the complete Table of Contents.
Sequerra, E. B., Costa, M. R., Menezes, J. R. L. and Hedin-Pereira, C. (2013). Adult neural stem cells: plastic or restricted cell fates? Development 140, 3303-3309.
Boyd, R. L., Soh, C. L., Boyd, N. R., Stanley, E. G. and Chidgey, A. P. (2013). Rewiring immunity: generating a functional thymus from hESCs... Are we there yet? Cell Stem Cell 13, 135-136.
Refers to Parent et al., 2013 and Sun et al., 2013 .
Goodell, M. A. (2013). Parental permissions: H19 and keeping the stem cell progeny under control. Cell Stem Cell 13, 137-138.
Refers to Venkatraman et al., 2013
Yoshioka, N., Gros, E., Li, H. R., Kumar, S., Deacon, D. C., Maron, C., Muotri, A. R., Chi, N. C., Fu, X. D., Yu, B. D. Dowdy, S. F. (2013). Efficient generation of human iPSCs by a synthetic self-replicative RNA . Cell Stem Cell 13, 246-254.
Alunni, A., Krecsmarik, M., Bosco, A., Galant, S., Pan, L., Moens, C. B. and Bally-Cuif, L. (2013). Notch 3 signalling gates cell cycle entry and limits neural stem cell amplification in the adult pallium. Development 140, 3335-3347.
Gonzalez-Cordero, A., West, E. L., Pearson, R. A., Duran, Y., Carvalho, L. S., Chu, C. J., Naeem, A., Blackford, S. J. I., Georgiadis, A., Lakowski, J., Hubank, M., Smith, A. J., Bainbridge, J. W. B., Sowden, J. C. and Ali, R. R. (2013). Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina. Nat Biotechnol 31, 741-747.
Hou, P., Li, Y., Zhang, X., Liu, C., Guan, J., Li, H., Zhao, T., Ye, J., Yang, W., Liu, K., Ge, J., Xu, J., Zhang, Q., Zhao, Y. and Deng, H. (2013). Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science 341, 651-654.
Kusuma, S., Shen, Y. I., Hanjaya-Putra, D., Mali, P., Cheng, L. and Gerecht, S. (2013). Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix. Proc Natl Acad Sci USA 110, 12601-12606.
Parent, A. V. , Russ, H. A., Khan, I. S., LaFlam, Metzger, T. C., Anderson, M. S. and Hebrok, M. (2013). Generation of functional thymic epithlium from human embryonic stem cells that supports host T cell development. Cell Stem Cell 13, 219-229.
Pereira, C. F., Chang, B., Qiu, J., Niu, X., Papatsenko, D., Hendry, C. E., Clark, N. R., Nomura-Kitabayashi, A., Kovacic, J. C., Ma'ayan, A., Schaniel, C., Lemischka, I. H. and Moore, K. (2013). Induction of a hemogenic program in mouse fibroblasts. Cell Stem Cell 13, 205-218.
Samuel, R., Daheron, L., Liao, S., Vardam, T., Kamoun, W. S., Batista, A., Buecker, C., Schäfer, R., Han, X., Au, P., Scadden, D. T., Duda, D. G., Fukumura, D. and Jain, R. K., (2013). Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells. Proc Natl Acad Sci USA 110, 12774-12779.
Sun, X., Xu, J., Lu, H., Liu, H., Miao, Z., Sui, X., Liu, H., Su, L., Du, W., He, Q., Chen, F., Shi, Y. and Deng, H. (2013). Directed differentiation of human embryonic stem cells into thymic epithelial progenitor-like cells reconstitutes the thymic microenvironment in vivo. Cell Stem Cell 13, 230-236.
Venkatraman, A ., He, X. C., Thorvaldsen, J. L., Sugimura, R., Perry, J. M., Tao, F., Zhao, M., Christenson, M. K., Sanchez, R., Yu, J. Y., Peng, L., Haug, J. S., Paulson, A., Li, H., Zhong, X. B., Clemens, T. L., Bartolomei, M. S. and Li, L. (2013). Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence. Nature doi:10.1038/nature12303.
Zhang, R. R., Cui, Q. Y., Murai, K., Lim, Y. C., Smith, Z. D., Jin, S., Ye, P., Rosa, L., Lee, Y. K., Wu, H. P., Liu, W., Xu, Z. M., Yang, L., Ding, Y. Q., Tang, F., Meissner, A., Ding, C., Shim Y. and Xu, G. L. (2013). Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell 13, 237-245.