|This issue is sponsored by:|
|1. Editor's Message
Carl Wonders, PhD
Welcome to Boston, Massachusetts! The ISSCR 11th Annual Meeting is set to begin tomorrow, June 12, with a fantastic lineup of speakers, posters, exhibitors and other programming. Not yet registered? On-site registration is available through Saturday, June 15. If you have already registered, be sure to take advantage of the various program-planning tools we have available. See Section 2 for more information.
The inaugural issue of Stem Cell Reports, the ISSCR’s new online, open-access journal was published on Wednesday, June 5, 2013. Check out the journal’s website today and peruse the fantastic group of articles covering a wide spectrum of stem cell research. As an added bonus, everyone attending the ISSCR 11th Annual Meeting will receive a print copy of the issue. See Section 7 for a complete table of contents.
Public Forum: "Stem Cell Stories: Revolutionary Results from Boston-area Researchers," presented by the Harvard Stem Cell Institute in association with the ISSCR. On Tuesday, June 11, 6 - 7:30 p.m., scientists from Harvard-affiliated labs presented their latest work to the public. The ISSCR thanks and congratulates HSCI and the presenters for putting on an excellent event and thanks all who attended and asked questions of the panel.
ISSCR Connect. Once again this year, we will be re-broadcasting select sessions from Boston on ISSCR Connect, the ISSCR’s online educational portal. As we finalize the schedule of content release , we will make that information available on the ISSCR Connect webpage.
ISSCR Regional Forum Series. In addition to the excellent science being presented this week in Boston, the ISSCR will be holding two additional Regional Forums in 2013. Abstract Submission and Registration are now open for both Forums; see Section 3 for more information!
Reach 14,000 - Sponsor The Pulse e-Newsletter. Did you know each month an exclusive sponsorship with ad space is available for the ISSCR's e-newsletter, The Pulse? This month’s sponsor, STEMCELL Technologies, benefits from exposure to more than 14,000 stem cell researchers, clinicians, regulatory officials, industry representatives, government authorities and others with an interest in stem cell research. Contact Amy Claver to reserve your space at the top of The Pulse.
|2. ISSCR 11th Annual Meeting
ISSCR 11th Annual Meeting
June 12-15, 2013
Boston, Massachusetts, USA
Co-sponsored by the Harvard Stem Cell Institute
|Tuesday, June 11
||2:00 PM – 6:00 PM
|Wednesday, June 12
||7:30 AM – 8:00 PM
|Thursday, June 13
||7:30 AM – 6:00 PM
|Friday, June 14
||7:30 AM – 5:00 PM
|Saturday, June 15
||8:00 AM – 5:00 PM
It's not too late to join us in Boston! On-site registration is now available, both online and in-person at the registration desks in the Boston Conference and Exhibition Center (BCEC). The registration desk hours of operations are given here for your convenience. Can't commit to the full meeting? Single-day registration is also available. For more information, visit our website or stop by the registration desk.
Planning in Boston.
With all of the speakers, posters and other sessions happening this year, it's more important than ever to plan your itinerary ahead of time. We have provided several tools for you to use to decide how to spend your time at the meeting.
As in previous years, the web-based Program Planner can be used to browse the sessions and to search for and identify those abstracts and talks you wish to see. If you are a registrant of the Annual Meeting, a link to the Program Planner will have been mailed to you. You can also see the "What To Know Before You Go" email for the link.
NEW for 2013: ISSCR2013 Mobile App. In addition to the web-based program planner, this year we are offering an additional way to build and check your itinerary on the go. The new ISSCR2013 Mobile App gives you access to your itinerary and the abstracts from your Apple or Android device. The Mobile App can also sync any abstracts or sessions you have already selected using the web-based Program Planner. Note: we recommend that you perform this sync after you have used the web-based Program Planner, as changes you make on the Mobile App will not be reflected online. Directions for downloading the Mobile App have been provided via email to registrants of the Annual Meeting and are also available in the “What To Know Before You Go” email.
Meet-Ups. These informal gatherings are occurring during the afternoon refreshment breaks on Thursday, June 13 and Friday, June 14. Visit the designated areas in the Exhibit Hall and join the discussions with your colleagues. For this year’s meeting, the following Meet-Ups have been scheduled:
|Thursday, June 13, 3:05 - 4:00 pm
|Florence Hub (#1)
Meet the Editors from Stem Cell Reports
|Suzhou Hub (#2)
Developmental Biology and Stem Cells; organized by Development
|Friday, June 14, 3:05 - 4:00 pm
|Florence Hub (#1)
German Stem Cell Network
|Suzhou Hub (#2)
Current Protocols in Stem Cell Biology
|Singapore Hub (#3)
Stem Cell Society Singapore
Wednesday Morning Special Sessions
If you are in Boston already and are registered for the meeting, consider attending these special sessions being held Wednesday morning before the start of the meeting. Access to these events is included with your registration at no extra charge.
Industry Wednesday Symposia – These sessions give companies the opportunity to present topical scientific issues in stem cell science as framed by industry leaders. For this year’s meeting, the following sessions are scheduled:
Focus Sessions are member-organized presentations that offer parallel, in-depth educational opportunities and explore unique issues relating to stem cell research. This year, we are pleased to present the following two sessions:
Junior Investigator Events
Each year at the ISSCR Annual Meeting, junior investigators have the opportunity to participate in specific networking, career-building and social events. These events are available at no extra charge to meeting attendees; however, separate registration is required as space is limited. If you have not yet registered, see the registration desk to check for remaining availability.
Are you on Twitter? Follow us @isscr to stay up to date on the latest Annual Meeting and ISSCR news. Use the hashtag #ISSCR2013 to follow and join in on the conversation all the way through the meeting.
Finally, we would like to acknowledge and thank all of the supporters of the ISSCR 11th Annual Meeting who make all of what we offer possible.
The Albert Einstein College of Medicine
American Society for Gene and Cell Therapy
Boston Children’s Hospital/Stem Cell Program
California Institute for Regenerative Medicine (CIRM)
European Society for Gene and Cell Therapy
F. Hoffmann-La Roche Ltd.
Ruth L. and David S. Gottesman Institute for Stem Cell Biology and Regenerative Medicine
Lieber Institute for Brain Development
Massachusetts General Hospital/Center for Regenerative Medicine
McGowan Institute for Regenerative Medicine at the University of Pittsburgh
The New York Stem Cell Foundation
Ontario Stem Cell Initiative (OSCI)
|3. Regional Forum Series 2013
For 2013, the ISSCR is expanding the global reach of our educational programming with two events presented as a part of the 2013 Regional Forum Series. These Regional Forums are designed to complement the ISSCR Annual Meeting by offering a more focused look at specific topics within stem cell research presented in more intimate settings.
Registration, Housing and Abstract Submission are now open!
The ISSCR invites you to Florence, Italy for Stem Cells in Translation, September 15-18, 2013, reflecting the major role of European research centers in the exciting transition of stem cell research to clinical relevance.
Highlight your work by submitting an abstract for a poster presentation.
Registration and housing are two separate processes:
- Register now to receive the early registration discount.
- Then proceed to reserve your room at an ISSCR preferred hotel.
The ISSCR is pleased to return to Suzhou and again partner with Cold Spring Harbor Asia to present Stem Cells in Science and Medicine. The diverse program offers a wide range of stem cell topics including Stem Cells & Development, iPS and Reprogramming, Cancer Stem Cells and Therapy and more. View the complete list of sessions and confirmed speakers.
Registration and abstract submission for this meeting is now open through the Cold Spring Harbor Asia website. Please note that you must register for the meeting first if you wish to submit an abstract – you will be given a link and instructions for abstract submission in your registration confirmation email.
More information on this meeting including travel and hotel information is available on the Forum website.
|4. Job Opportunities
Seeking a job? Have a job opening? Visit the ISSCR Job Bank. ISSCR members receive a discount on job postings.
Looking for increased exposure for your job opening? Upgrade to a Featured Job, and receive a special mention here in The Pulse.
|5. Funding and Awards
See below for a selected list of upcoming funding opportunities. Visit the Funding Corner of the ISSCR website for additional opportunities, more information or to plan ahead.
EuroStemCell non-fiction writing competition. Submit your work in one of three categories: imaginative science writing, graphic non-fiction and non-fiction poetry. Read more, including the eligibility criteria, judging criteria and prizes. The submission deadline is June 30, 2013.
California Institute for Regenerative Medicine (CIRM)
View a list of current Requests for Applications.
The Center for the Advancement of Science in Space (CASIS) has issued a Request for Proposals (RFP) seeking to identify projects within the field of mammalian stem cell biology. Read the full RFP.
The International Eppendorf & Science Prize for Neurobiology honors young scientists for their outstanding contributions to neurobiological research based on methods of molecular and cell biology. One prize of $25,000 (US) is awarded each year, and the due date for this year’s application is June 15, 2013.
European Molecular Biology Organisation (EMBO)
Short- (up to three months) and Long- (1-2 years) Term Fellowships are currently available.
Long-Term Fellowship – offered twice a year to individuals holding a PhD with less than three years of postdoctoral training. Next deadline: August 15, 2013
Short-Term Fellowship – offered on a year-round basis to pre-doctoral students and individuals holding a PhD with less than 10 years of postdoctoral training.
National Institute of Mental Health - new funding opportunity announcement (FOA) applications for an academic-industrial partnership to use iPS, iN or similar reprogrammed cells. Read the full announcement. The next letter of intent deadline is August 26, 2013.
Wellcome Trust (UK)
The Wellcome Trust is a UK-based organization that funds research to improve human and animal health. The Wellcome Trust supports research conducted outside the UK where research develops international partnerships, or focuses on biomedical or clinical medicine in developing countries. See their list of funding opportunities. In addition, view a complete list of upcoming deadlines.
|6. Meetings and Courses
Visit the ISSCR's online events calendar for a complete listing of meetings and courses.
ISSCR 11th Annual Meeting
International Conference 2013
Co-sponsored by HSCI and ISSCR
June 12-15, 2013
Boston, MA, USA
Stem Cells in Translation
ISSCR 2013 Regional Forum Series
Sept. 15 - 18, 2013
Palazzo dei Congressi
Stem Cells in Science and Medicine
ISSCR 2013 Regional Forum Series
Co-produced by ISSCR and Cold Spring Harbor Asia
Oct. 14-18, 2013
Stem Cell Meetings
17th International Congress of Developmental Biology
June 16 - 20, 2013
eCM XIV: Stem & Progenitor Cells for Musculoskeletal Regeneration
June 23 – 25, 2013
Abstract Submission Deadline: April 8, 2013
Discounted Registration Deadline: June 1, 2013
MSC2013: Adult Stem Cell Therapy and Regenerative Medicine
August 19 - 21, 2013
Cleveland, OH USA
ISEH - 42nd Annual Scientific Meeting
Aug. 22 - 25, 2013
Abstract submission deadline: April 12, 2013
Discounted registration deadline: June 3, 2013
2013 Shanghai International Symposium on Cancer Stem Cells
Oct. 17 - 19, 2013
Tongji University, Shanghai, China
Abstract Submission Deadline: August 1, 2013
Stem Cell Courses
Human iPSC Derivation and Culture
June 9 - 11, 2013
Harvard University, Harvard Stem Cell Institute iPS Core Faciltity
Room B01, 7 Divnity Avenue
Cambridge, Massachusetts, USA
Application Deadline: June 4, 2013
The 21st School in Life Sciences: Stem Cells and Regenerative Biology
July 21-25, 2013
The Hebrew University of Jerusalem
Application Deadline: May 31, 2013
EMBO Practical Course: Current methods in cell biology
Sept. 26 - Oct. 4, 2013
Regularly Occurring Courses
Cellular Dynamics International (CDI): iCertification Courses
Madison, WI, USA
Two-day training courses for CDI's iCell Products.
Life Technologies: LifeLab Pluripotent Stem Cell Workshops
Various Locations, Global
Training in culturing and characterizing hESCs and iPSCs and reprogramming techniques offered at various locations throughout the year.
STEMCELL Technologies: Training Courses
Vancouver, BC, Canada
Ongoing series of a range of specialized stem cell courses.
|7. Literature Highlights
The inaugural issue of the ISSCR's new, open-access journal, Stem Cell Reports, is now available! Visit the Stem Cell Reports website or follow the links below to each individual paper.
Lensch, M. W. and Mummery, C. L. (2013). From stealing fire to cellular reprogramming: a scientific history leading to the 2012 Nobel Prize. Stem Cell Reports 1, 5-17
Gomez, C., Chua, W., Miremadi, A., Quist, S., Headon, D. J. and Watt, F. M. (2013). The interfollicular epidermis of adult mouse tail comprises two distinct cell lineages that are differentially regulated by Wnt, Edaradd, and Lrig1. Stem Cell Reports 1, 19-27.
Kannan, N., Huda, N., Tu, L., Droumeva, R., Aubert, G., Chavez, E., Brinkman, R. R., Lansdorp, P., Emerman, J., Abe, S., Eaves, C. and Gilley, D. (2013). The luminal progenitor compartment of the normal human mammary gland constitutes a unique site of telomere dysfunction. Stem Cell Reports 1, 28-37.
Johnston, A. P. W., Naska, S., Jones, K., Jinno, H., Kaplan, D. R. and Miller, F. D. (2013) Sox2-mediated regulation of adult neural crest precursors and skin repair. Stem Cell Reports 1, 38-45.
Jiang, W., Zhang, D., Bursac, N. and Zhang, Y. (2013). WNT3 is a biomarker capable of predicting the definitive endoderm differentiation potential of hESCs. Stem Cell Reports 1, 46-52.
Gertow, K., Hirst, C. E., Yu, Q. C., Ng, E. S., Pereira, L. A. Davis, R. P., Stanley, E. G. and Elefanty, A. G. (2013). WNT3A promotes hematopoietic or mesenchymal differentiation from hESCs depending on the time of exposure. Stem Cell Reports 1, 53-65.
Leitch, H. G., Nichols, J., Humphreys, P., Mulas, C., Martello, G., Lee, C., Jones, K., Surani, M. A. and Smith, A. (2013). Rebuilding pluripotency from primordial germ cells. Stem Cell Reports 1, 66-78.
Stelzer, Y., Ronen, D., Bock, C., Boyle, P., Meissner, A. and Benvenisty, N. (2013). Identification of novel imprinted differentially methylated regions by global analysis of human-parthenogenetic-induced pluripotent stem cells. Stem Cell Reports 1, 79-89.
Khattak, S., Schuez, M., Richter, T., Knapp, D., Haigo, S. L., Sandoval-Guzmán, Hradlikova, K., Duemmier, A., Kerney, R. and Tanaka, E. M. (2013). Germline transgenic methods for tracking cells and testing gene function during regeneration in the Axolotl. Stem Cell Reports 1, 90-103.
In addition to the excellent content the ISSCR has to offer in Stem Cell Reports, we will continue to highlight other recently published articles here:
Borgelt, E. L., Dharamsi, S. and Scott, C. T. (2013). Dear student: stem cell scientists’ advice to the next generation. Cell Stem Cell 12, 652-655.
Kim, Y. J. and Lee, G. (2013). Candidate ALS therapeutics motor toward “in vitro clinical trials.” Cell Stem Cell 12, 633-634.
Refers to Yang et al., 2013.
Trounson, A. and DeWitt, N. D. (2013). Pluripotent stem cells from cloned human embryos: success at long last. Cell Stem Cell 12, 636-638.
Refers to Tachibana et al., 2013.
Garcia, I., Kim, C. and Arenkiel, B. R. (2013). Revealing neuronal circuitry using stem cell-derived neurons. Curr Protoc Stem Cell Biol. 25:2D.15.1–2D.15.18.
Ibrahim, E. E., Babaei-Jadidi, R. and Nateri, A. S. (2013). The streptavidin/biotinylated DNA/protein bound complex protocol for determining the association of c-JUN protein with NANOG promoter. Curr Protoc Stem Cell Biol. 25:1B.10.1–1B.10.13.
Parker, M. H. and Tapscott, S. J. (2013). Expanding donor muscle-derived cells for transplantation. Curr Protoc Stem Cell Biol.25:2C.4.1–2C.4.16.
Putman, D. M. and Hess, D. A. (2013). Isolation of Human Umbilical Cord Blood Aldehyde Dehydrogenase–Expressing Progenitor Cells that Modulate Vascular Regenerative Functions In Vitro and In Vivo. Curr Protoc Stem Cell Biol. 25:2A.10.1–2A.10.19.
Yamanaka, S., Wagers, A., Muotri, A., Srivastava, D., Melton, D., Blanpain, C., Gurdon, J., Fuchs, E. and Jaenisch, R. (2013) Stem Cells in Translation. Cell 153, 1177-1179.
Sato, T. and Clevers H. (2013). Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 340, 1190-1194.
Schneider, R. P., Garrobo, I, Foronda, M., Placios, J. A., Marión, R. M., Flores, I., Ortega, S., Blasco, M. A. (2013). TRF1 is a stem cell marker and is essential for the generation of induced pluripotent stem cells. Nat Commun doi:10.1038/ncomms2946.
Sridharan, R., Gonzales-Cope, M., Chronis, C., Bonora, G., McKee, R., Huang, C., Patel, S., Lopez, D., Mishra, N., Pellegrini, M., Carey, M., Garcia, B. A. and Plath, K. (2013). Proteomic and genomic approaches reveal critical functions of H3K9 methylation and herterochromatin protein-1γ in reprogramming to pluripotency. Nat Cell Biol doi:10.1038/ncb2768.
Tachibana, M., Amato, P., Sparman, M., Gutierrez, N. M., Tippner-Hedges, R., Ma, H., Kang, E., Fulati, A., Lee, H. S., Sritanaudomchai, H., Masterson, K., Larson, J., Eaton, D., Sadler-Fredd, K., Battaglia, D., Lee, D., Wu, D., Jensen, J., Patton, P., Gokhale, S., Stouffer, R. L., Wolf, D. and Mitalipov, S. (2013). Human embryonic stem cells derived by somatic cell nuclear transfer. Cell 153, 1228-1238.
Tulpule, A., Kelley, J. M., Lensch, M. W., McPherson, J., Park, I. H., Hartung, O., Nakamura, T., Schlaeger, T. M., Shimamura, A. and Daley, G. Q. (2013). Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction. Cell Stem Cell 12, 727-736.
Yang, Y. M., Gupta, S. K., Kim, K. J., Powers, B. E., Cerqueira, A., Wainger, B. J., Ngo, H. D., Rosowski, K. A., Schein, P. A., Ackeifi, C. A., Arvanites, A. C., Davidow, L. S., Woolf, C. J. and Rubin, L. L. (2013). A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS. Cell Stem Cell 12, 713-726.