|This issue is sponsored by:|
|1. Editor's Message
Carl Wonders, PhD
There are only four weeks remaining until the start of the ISSCR 11th Annual Meeting in Boston, Massachusetts, USA! Save money and time spent in line by registering online today. Read the latest Annual Meeting updates, including information about the new electronic abstract book and meeting planner app in Section 2.
Public Forum: "Stem Cell Stories: Revolutionary Results from Boston-area Researchers," Tuesday, June 11, 6 - 7:30 p.m. presented by the Harvard Stem Cell Institute in association with the ISSCR. Join us at the Rooftop Ballroom of the Omni Parker House as scientists from Harvard-affiliated labs will present five-minute presentations on their latest work. This event is free and open to the public.
ISSCR 2013 Regional Forum Series. Registration and Abstract Submissions are now open for the two upcoming meetings in the ISSCR 2013 Regional Forum Series. See Section 3 for more information.
ISSCR Connect re-launches tomorrow with an all-new interface and programming. Tune in to the inaugural presentation of "What's New at the ISSCR" on Wednesday, May 15 at 10 AM EDT (USA), and see Section 4 for more information.
Stem Cell Reports. The first issue of ISSCR’s open-access journal debuts in one month! The academic editorial board, led by Editor-in-Chief Christine Mummery, have put together a terrific first issue, and all annual meeting attendees will receive a complementary printed copy of the inaugural edition on site. Visit the journal's website to learn more about Stem Cell Reports. Meet the Editors. Bring your questions and talk to the editors of Stem Cell Reports at the Annual Meeting. See Section 2 for more information.
The ISSCR Emphasizes Importance of Regulatory Oversight for Stem Cell Products for Clinical Use. With discussion within the Italian Parliament regarding the regulation of stem cell products, the ISSCR urges lawmakers to heed the concerns of the international scientific community over the use of unproven stem cell treatments. Read the complete statement.
Reach 14,000 – Sponsor The Pulse e-newsletter. Did you know each month an exclusive sponsorship with ad space is available for the ISSCR’s e-newsletter, The Pulse? This month’s sponsor, STEMCELL Technologies benefits from exposure to more than 14,000 stem cell researchers, clinicians, regulatory officials, industry representatives, government authorities and others with an interest in stem cell research. Contact Amy Claver to reserve your space at the top of The Pulse.
|2. ISSCR 11th Annual Meeting
ISSCR 11th Annual Meeting
June 12-15, 2013
Boston, Massachusetts, USA
Co-sponsored by the Harvard Stem Cell Institute
There is still time to register online! Save time spent in line at the registration desk and register online today.
NEW FOR 2013!
This year, the ISSCR 2013 Mobile App and Abstract eBook will replace the printed abstract books that have been used in the past. Now it will no longer be necessary to carry around heavy abstract books or manually search and highlight.
The new ISSCR2013 Mobile App, sponsored by Cellular Dynamics International, allows you to stay connected on the go. Compatible with the mobile device of your choice, this app allows you to customize your itinerary and access it on the go. Its search capabilities of the app allow you to easily find the scientific content, presenters, and exhibitors that you would like to hear or connect with. Drop the events, sessions, talks, or posters into your calendar to prepare a customized itinerary for each day. Be notified of any up-to-the minute updates and location information during the meeting.
As always, you can also use the Program Planner website to customize your itinerary. Afterwards, you candownload it to the ISSCR 2013 Mobile App.
Registered attendees will be alerted by email when the Program Planner tool is live and that the ISSCR 2013 mobile app is available for download.
See the updated schedule at a glance online to view the abstract-selected speakers and details of the concurrent sessions.
Registration is now open for the Junior Investigator events. Each year at the ISSCR Annual Meeting, junior investigators have the opportunity to participate in specific networking, career-building and social events. All eligible registrants will receive an email with instructions on how to register for the following events:
Wednesday pre-meeting scientific events. All registered attendees should plan to arrive early and be a part of these pre-meeting events scheduled for the morning of Wednesday, June 12. Admission to all of these events is included in your registration.
Industry Wednesday Symposia – These sessions give companies the opportunity to present topical scientific issues in stem cell science as framed by industry leaders. For this year’s meeting, the following sessions are scheduled:
Focus Sessions are member-organized presentations that offer parallel, in-depth educational opportunities and explore unique issues relating to stem cell research. This year, we are pleased to present the following two sessions:
Meet-Ups at the ISSCR Annual Meeting.
Sponsored by BD Biosciences
These informal discussion groups will take place in designated areas in the Exhibitin Hall during the refreshment breaks. Meet with collegues sharing common interests and make new connections. To date, the following Meet-Ups have been scheduled:
|Thursday Afternoon Hub #1
||Meet the Editors of Stem Cell Reports
|Thursday Afternoon Hub #2
||Stem Cells and Developmental Biology
organized by Development
|Friday Afternoon Hub #1
||German Stem Cell Network Meet-Up
|Schedule subject to change
See the latest technology, services and other stakeholders in the field of stem cell research and regenerative medicine in the exhibit hall. Find solutions and meet one-on-one with industry leaders. View the list of exhibiting companies on the ISSCR Annual Meeting website.
Is your company interested in supporting the ISSCR 11th Annual Meeting? Contact Amy Claver for more information.
Are you on Twitter? Follow us @isscr to stay up to date on the latest Annual Meeting and ISSCR news. Use the hashtag #ISSCR2013 to follow and join in on the conversation all the way through the meeting.
The ISSCR thanks its generous supporters who make the many events and offerings at the Annual Meeting possible.
The Albert Einstein College of Medicine
American Society for Gene and Cell Therapy
Boston Children’s Hospital/Stem Cell Program
The Company of Biologists
European Society for Gene and Cell Therapy
Ruth L. and David S. Gottesman Institute for Stem Cell Biology and Regenerative Medicine
Lieber Institute for Brain Development
Massachusetts General Hospital/Center for Regenerative Medicine
The New York Stem Cell Foundation
University of Pittsburgh, McGowan Institute for Regenerative Medicine
|3. ISSCR 2013 Regional Forum Series
For 2013, the ISSCR is expanding the global reach of our educational programming with two events presented as a part of the 2013 Regional Forum Series. These Regional Forums are designed to complement the ISSCR Annual Meeting by offering a more focused look at specific topics within stem cell research presented in more intimate settings.
Registration, Housing and Abstract Submission are now open!
The ISSCR invites you to Florence, Italy for Stem Cells in Translation, September 15-18, 2013, reflecting the major role of European research centers in the exciting transition of stem cell research to clinical relevance.
Highlight your work by submitting an abstract for a poster presentation.
Registration and housing are two separate processes:
- Register now to receive the early registration discount.
- Then proceed to reserve your room at an ISSCR preferred hotel.
The ISSCR is pleased to return to Suzhou and again partner with Cold Spring Harbor Asia to present Stem Cells in Science and Medicine. The diverse program offers a wide range of stem cell topics including Stem Cells & Development, iPS and Reprogramming, Cancer Stem Cells and Therapy and more. View the complete list of sessions and confirmed speakers.
Registration and abstract submission for this meeting is now open through the Cold Spring Harbor Asia website. Please note that you must register for the meeting first if you wish to submit an abstract – you will be given a link and instructions for abstract submission in your registration confirmation email.
More information on this meeting including travel and hotel information is available on the Forum website.
|4. ISSCR Connect
ISSCR Connect has an all-new look! Tomorrow, May 15, we will be re-launching ISSCR Connect with an all-new interface and new programming.
What's New at the ISSCR – a new monthly program discussing the latest developments within the ISSCR. Hear about new ISSCR programs, bring your questions and participate in the live chat and Q&A features!
The program begins at 10 am ET (USA). Calculate your local time
Can't make it? The program will be available on-demand after the broadcast
ISSCR Members – as one of your benefits to membership, you will automatically be registered for ISSCR Connect. You will receive an email containing your login and password.
Not yet a member? Create an account and receive access to the Public Channel.
|5. News Roundup
United Kingdom. Robert G. Edwards, the winner of the Nobel Prize for Physiology or Medicine in 2010 for the development of in vitro fertilization died on April 10, 2013, at the age of 87. Read more.
Italy. The Italian Chamber will vote soon on whether to proceed with a law passed by the Senate in March that would permit the administration of an unproven stem cell treatment to patients for a period of 18 months. Read more.
|6. Job Opportunities
Seeking a job? Have a job opening? Visit the ISSCR’s Job Bank. ISSCR members receive a discount on job postings.
Featured Job: Senior Research Manager, Harvard University, Dept of Stem Cell and Regenerative Biology. Providing scientific and administrative leadership for research programs in the HSCRB laboratory of Professor Lee Rubin, the senior research manager will collaborate with the Principal Investigator (PI) to develop long-range research program and promote lab environment that fosters innovative translational research. Read the full posting.
Featured Job: Preceptor of Stem Cell and Regenerative Biology, Harvard University. Responsible for overseeing and implementing undergraduate courses in the Harvard Department of Stem Cell and Regenerative Biology, this position is a non-ladder teaching position with a twelve-month appointment. Read the full posting.
|7. Funding and Awards
See below for a selected list of upcoming funding opportunities. Visit the Funding Corner of the ISSCR website for additional opportunities, more information or to plan ahead.
EuroStemCell non-fiction writing competition. Submit your work in one of three categories: imaginative science writing, graphic non-fiction and non-fiction poetry. Read more, including the eligibility criteria, judging criteria and prizes. The submission deadline is June 30, 2013.
California Institute for Regenerative Medicine (CIRM)
View a list of current Requests for Applications.
The International Eppendorf & Science Prize for Neurobiology honors young scientists for their outstanding contributions to neurobiological research based on methods of molecular and cell biology. One prize of $25,000 (US) is awarded each year, and the due date for this year’s application is June 15, 2013.
European Molecular Biology Organisation (EMBO)
Short- (up to three months) and Long- (1-2 years) Term Fellowships are currently available.
Long-Term Fellowship – offered twice a year to individuals holding a PhD with less than three years of postdoctoral training. Next deadline: August 15, 2013
Short-Term Fellowship – offered on a year-round basis to pre-doctoral students and individuals holding a PhD with less than 10 years of postdoctoral training.
Wellcome Trust (UK)
The Wellcome Trust is a UK-based organization that funds research to improve human and animal health. The Wellcome Trust supports research conducted outside the UK where research develops international partnerships, or focuses on biomedical or clinical medicine in developing countries. See their list of funding opportunities. In addition, view a complete list of upcoming deadlines.
Sir Henry Wellcome Postdoctoral Fellowship: May 20, 2013
|8. Events and Courses
Visit the ISSCR's online events calendar for a complete listing of meetings and courses.
ISSCR 11th Annual Meeting
International Conference 2013
Co-sponsored by HSCI and ISSCR
June 12-15, 2013
Boston, MA, USA
Stem Cells in Translation
ISSCR 2013 Regional Forum Series
Sept. 15 - 18, 2013
Palazzo dei Congressi
Stem Cells in Science and Medicine
ISSCR 2013 Regional Forum Series
Co-produced by ISSCR and Cold Spring Harbor Asia
Oct. 14-18, 2013
Stem Cell Meetings
V. Else Kröner-Fresenius Symposium on Adult Stem Cells in Aging, Diseases, and Cancer
May 24 - 26, 2013
Abstract Submission Deadline: February 15, 2013
Registration Closes: March 15, 2013
The Clinical Science of Regenerative Neurology
May 30 - 31, 2013
Edinburgh, Scotland, UK
Discounted Registration Deadline: March 1, 2013
Poster Presentation Submission Deadline: April 1, 2013
New Avenues for Brain Repair: Programming and Reprogramming the Central Nervous System
June 10 - 11, 2013
Boston, MA USA
Abstract submission deadline: March 15, 2013
Discounted registration deadline: April 5, 2013
Poster abstract submission deadline: April 5, 2013
17th International Congress of Developmental Biology
June 16 - 20, 2013
eCM XIV: Stem & Progenitor Cells for Musculoskeletal Regeneration
June 23 – 25, 2013
Abstract Submission Deadline: April 8, 2013
Discounted Registration Deadline: June 1, 2013
MSC2013: Adult Stem Cell Therapy and Regenerative Medicine
August 19 - 21, 2013
Cleveland, OH USA
ISEH - 42nd Annual Scientific Meeting
Aug. 22 - 25, 2013
Abstract submission deadline: April 12, 2013
Discounted registration deadline: June 3, 2013
2013 Shanghai International Symposium on Cancer Stem Cells
Oct. 17 - 19, 2013
Tongji University, Shanghai, China
Abstract Submission Deadline: August 1, 2013
Stem Cell Courses
Human iPSC Derivation and Culture
June 9 - 11, 2013
Harvard University, Harvard Stem Cell Institute iPS Core Faciltity
Room B01, 7 Divnity Avenue
Cambridge, Massachusetts, USA
Application Deadline: June 4, 2013
The 21st School in Life Sciences: Stem Cells and Regenerative Biology
July 21-25, 2013
The Hebrew University of Jerusalem
Application Deadline: May 31, 2013
EMBO Practical Course: Current methods in cell biology
Sept. 26 - Oct. 4, 2013
Regularly Occurring Courses
Cellular Dynamics International (CDI): iCertification Courses
Madison, WI, USA
Two-day training courses for CDI's iCell Products.
Life Technologies: LifeLab Pluripotent Stem Cell Workshops
Various Locations, Global
Training in culturing and characterizing hESCs and iPSCs and reprogramming techniques offered at various locations throughout the year.
STEMCELL Technologies: Training Courses
Vancouver, BC, Canada
Ongoing series of a range of specialized stem cell courses.
|9. Literature Highlights
Bianco, P., Barker, R., Brüstle, O., Cattaneo, E., Clevers, H., Daley, G. Q., De Luca, M., Goldstein, L., Lindvall, O., Mummery, C., Robey, P. G., Sattler de Sousa E Brito, C., Smith, A. (2013). Regulation of stem cell therapies under attack in Europe: for whom the bell tolls. EMBO J doi:10.1038/emboj.2013.114.
Hyun, I. (2013). Therapeutic hope, spiritual distress, and the problem of stem cell tourism. Cell Stem Cell 12, 505-507.
Underwood, E. (2013). Tissue imaging method makes everything clear. Science 340, 131-132.
Goldman, S. A. (2013). White matter from fibroblasts. Nat Biotechnol 31, 412-413.
refers to Najm et al., 2013 and Yang et al.,2013
Leinwand, L. A. and Harrison, B. C. (2013). Young at heart. Cell 153, 743-745.
refers to Loffredo et al.,2013
Marin, O. (2013). Human cortical interneurons take their time. Cell Stem Cell 12, 497-499.
refers to Maroof et al., 2013 and Nicholas et al., 2013
Behar, R. Z., Bahl, V., Wang, Y., Weng, J.-H., Lin, S. C. and Talbot, P. (2012). Adaptation of Stem Cells to 96-Well Plate Assays: Use of Human Embryonic and Mouse Neural Stem Cells in the MTT Assay. Curr. Protoc. Stem Cell Biol. 23:1C.13.1–1C.13.21.
McKeithan, W. L., Colas, A. R., Bushway, P. J., Ray, S. and Mercola, M. (2012). Serum-Free Generation of Multipotent Mesoderm (Kdr+) Progenitor Cells in Mouse Embryonic Stem Cells for Functional Genomics Screening. Curr. Protoc. Stem Cell Biol.23:1F.13.1–1F.13.13.
Herlenius, E., Thonabulsombat, C., Forsberg, D., Jäderstad, J., Jäderstad, L. M., Björk, L. and Olivius, P. (2012). Functional Stem Cell Integration Assessed by Organotypic Slice Cultures. Curr. Protoc. Stem Cell Biol. 23:2D.13.1–2D.13.26.
Wang, A. and Gee Liew, C. (2012). Genetic Manipulation of Human Induced Pluripotent Stem Cells. Curr. Protoc. Stem Cell Biol.. 23:5B.2.1–5B.2.9.
Ramos, A. D., Diaz, A., Nellore, A., Delgado, R. N., Park, K. Y., Gonzales-Roybal, G., Oldham, M. C., Song, J. S. and Lim, D. A. (2013). Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo. Cell Stem Cell 12, 616-628
Heredia, J. E., Makundan, L., Chen, F. M., Mueller, A. A., Deo, R. C., Locksley, R. M., Rando, T. A. and Chawla, A. (2013). Type 2 innate signals simulate fibro/adipogenic progenitors to facilitate muscle regeneration. Cell 153, 376-388.
Karwacki-Neisius, V., Göke, J., Osorno, R., Halbritter, F., Ng, J. H., Weiße, A. Y., Wong, F. C. K., Gagliardi, A., Mullin, N. P., Festuccia, N., Colby, D., Tomlinson, S. R., Ng, H. H. and Chambers, I. (2013). Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog. Cell Stem Cell 12, 531-545.
Liu, Y., Weick, J. P., Liu, H., Krenick, R., Zhang, X., Ma, L., Zhou, G., Ayala, M. and Zhang, S. C. (2013). Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits. Nat Biotechnol 31, 440-447.
Loffredo, F. S., Steinhauser, M. L., Jay, S. M., Gannon, J., Pancoast, J. R., Yalamanchi, P., Sinha, M., Dall’Osso, C., Khong, D., Shadrach, J. L., Miller, C. M., Singer, B. S., Stewart, A., Psychogios, N., Gerszten, R. E., Hartigan, A. J., Kim, M. J., Serwold, T., Wagers, A. J. and Lee, R. T. (2013). Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy. Cell 153, 828-839.
Maroof, A. M., Keros, S., Tyson, J. A., Ying, S. W., Ganat, Y. M., Merkle, F. T., Liu, B., Goulburn, A., Stanley, E. G., Elefanty, A. G., Widmer, H. R., Eggan, K., Goldstein, P. A., Anderson, S. A. and Studer, L. (2013). Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell 12, 559-572.
Najm, F. J., Lager, A. M., Zaremba, A., Wyatt, K., Caprariello, A. V., Factor, D. C., Karl, R. T., Maeda, T., Miller, R. H. and Tesar, P. J. (2013). Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells. Nat Biotechnol 31, 426-433.
Nicholas, C. R., Chen, J., Tang, Y., Southwell, D. G., Chalmers, N., Vogt, D., Arnold, C. M., Chen, Y. J. J., Stanley, E. G., Elefanty, A. G., Sasai, Y., Alvarez-Buylla, A., Rubenstein, J. L. R. and Kriegstein, A. R. (2013). Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development. Cell Stem Cell 12, 573-586.
Yang, N., Zuchero, J. B., Ahlenius, H., Marro, S., Ng, Y. H., Vierbuchen, T., Hawkins, J. S., Geissler, R., Barres, B. A. and Wernig, M. (2013). Generation of oligodendroglial cells by direct lineage conversion. Nat Biotechnol 31, 434-439.
Yi, P., Park, J. S. and Melton, D. A. (2013). Betatrophin: a hormone that controls pancreatic β cell proliferation. Cell 153, 747-758.