|This issue is sponsored by:|
|1. Editor's Message
April 17 is the last day for the Early Bird Discount for the ISSCR 11th Annual Meeting, Boston, Massachusetts, USA, June 12-15, 2013, co-sponsored by the Harvard Stem Cell Institute (HSCI). Read Section 2 for details on how to register and information about the meeting program.
ISSCR 2013 Elections. The results of the ISSCR 2013 Board of Directors elections have been announced. Read Section 3 to learn more about the results and to meet the incoming vice-president, treasurer and board member.
ISSCR 2013 Regional Forum Series. Join the ISSCR in September and October for two regional conferences as part of the ISSCR 2013 Regional Forum Series. Visit the newly launched websites for both conferences and read more in Section 4.
Coming in June: the inaugural issue of Stem Cell Reports. Under the editorship of Professor Christine Mummery, PhD, Leiden University Medical Center, the ISSCR’s new open-access journal, Stem Cell Reports, will publish its inaugural issue this June. All registrants of the ISSCR 11th Annual Meeting will receive a complimentary copy of the issue. Read more in Section 9 or visit the Stem Cell Reports website.
Changes are coming to ISSCR Connect! We are currently hard at work making changes to the ISSCR Connect platform. ISSCR Connect will relaunch in late April in anticipation of the upcoming Annual Meeting with a new look and other enhancements. Check your inbox for more details coming soon.
The ISSCR reiterates concerns regarding the recent decision in Italy to permit the use of unproven stem cell treatments. The ISSCR further emphasizes the critical role played by independent review and oversight in the development of treatments. Read the full ISSCR statement.
Reach 14,000 – Sponsor The Pulse e-newsletter. Did you Did you know each month an exclusive sponsorship with ad space is available for the ISSCR's e-newsletter, The Pulse? By sponsoring this month's e-newsletter, STEMCELL Technologies benefits from exposure to more than 14,000 stem cell researchers, clinicians, regulatory officials, industry representatives, government authorities and others with an interest in stem cell research. Contact Amy Claver to reserve space for select upcoming issues.
|2. ISSCR 11th Annual Meeting
ISSCR 11th Annual Meeting
June 12-15, 2013
Boston, Massachusetts, USA
Co-sponsored by the Harvard Stem Cell Institute
|Early Registration Deadline
|Housing Service Deadline
|Deadline to Join and Register at Member Rate
April 17 is the final day of the Early Bird Discount! Rates go up after April 17, so this is your last opportunity to save up to $120 on the cost of registering for the ISSCR 11th Annual Meeting. Members of the ISSCR receive the greatest discount on registration: if you’re not yet a member, join today and immediately receive the member registration rate. Contact Rico Blanco (email@example.com; +1-224-592-5756) with questions.
Plan your stay in Boston! Rooms have been set aside at negotiated rates for registrants of the ISSCR Annual Meeting. Space is limited, and these hotels are filling up quickly, so register and book early.
Abstract and Travel Award Notification. Email notifications have been sent to presenting authors of their abstract placement. A separate email will be sent to Travel Award recipients by Wednesday, April 10. If you have any questions, please contact Liz Weislogel(firstname.lastname@example.org; +1-224-592-5752).
Junior Investigator-specific events. Each year at the ISSCR Annual Meeting, Junior Investigators have the opportunity to participate in specific networking, career-building and social events. For 2013, the following events are available to registered Junior Investigators:
Pre-meeting scientific events. All registered attendees are invited to arrive early, attend and participate in these pre-meeting scientific events scheduled from 8:30 a.m. – 12:30 p.m. the morning of Wednesday, June 12:
- Industry Wednesday Symposia – These sessions give companies the opportunity to present topical scientific issues in stem cell science as framed by industry leaders. ThermoFisher has already committed to present, and other companies are expected to confirm soon. Space is limited – if your company is interested in participating or would like more information, contact Amy Claver or Drew Rich today!
- Focus Sessions are member-organized presentations that offer parallel, in-depth educational opportunities and explore unique issues relating to stem cell research.
The ISSCR Ethics and Public Policy Committee will be presenting a Focus Session discussing the current challenges and future directions facing the donation of somatic cells for stem cell research purposes.
Stem CEll COREdinates and the Allen Institute of Brain Science are collaborating on a session entitled "Generating collections of human iPSC and ES lines; Estabishing best practices for sharing protocols and cell lines."
See the latest technology, services and other stakeholders in the field of stem cell research and regenerative medicine in the exhibit hall. Find solutions and meet one-on-one with industry leaders. View the list of exhibiting companies on the ISSCR Annual Meeting website.
Is your company interested in supporting the ISSCR 11th Annual Meeting? Contact Amy Claver for more information.
Are you giving a talk in the near future? Help us spread the word by using the ISSCR 11th Annual Meeting PowerPoint® slide in your next presentation.
Are you on Twitter? Follow us @isscr to stay up to date on the latest Annual Meeting and ISSCR news. Use the hashtag #ISSCR2013 to follow and join in on the conversation all the way through the meeting.
The ISSCR thanks its generous supporters who make the many events and offerings at the Annual Meeting possible.
The Albert Einstein College of Medicine
American Society for Gene and Cell Therapy
Boston Children’s Hospital/Stem Cell Program
The Company of Biologists
European Society for Gene and Cell Therapy
Ruth L. and David S. Gottesman Institute for Stem Cell Biology and Regenerative Medicine
Lieber Institute for Brain Development
Massachusetts General Hospital/Center for Regenerative Medicine
The New York Stem Cell Foundation
University of Pittsburgh, McGowan Institute for Regenerative Medicine
|3. ISSCR 2013 Election Results
This year’s elections for the ISSCR Officers and Board of Directors closed on March 20, with more than 27% of eligible members voting. Read more about the winners and see the list of current ISSCR Board of Directors members.
The ISSCR thanks outgoing board members Thomas Graf, PhD (Spain), Derek van der Kooy, PhD (Canada) and Fiona Watt, DPhil (UK) for their valuable contributions to the society and welcomes both the new and returning members of the Board of Directors. The new term will begin following the ISSCR 11th Annual Meeting, June 11-15, 2013.
Sean Morrison, PhD, UT Southwestern, Dallas, Texas, USA, has been elected the new vice president of the ISSCR. Dr. Morrison will serve as the vice president for the upcoming term, after which he will become the president-elect for a term and then president of the ISSCR in his third year. He will then serve a fourth year as the immediate past president. Dr. Morrison will become the ISSCR president following the ISSCR 13th Annual Meeting in Stockholm, Sweden in 2015.
Haifan Lin, PhD, Yale Stem Cell Center, New Haven, Connecticut, USA, has been elected to the executive position of treasurer of the ISSCR. Dr. Lin has previously served as a member of the ISSCR Board of Directors and was the Program Committee Chair for the ISSCR 9th Annual Meeting. His term as treasurer will be for three years.
Urban Lendahl, PhD (Sweden) will be joining the Board of Directors as a new appointment, while Hans Clevers, PhD (Netherlands), Hongkui Deng, PhD (China) and Amy Wagers, PhD (USA) have all been re-appointed for a second term.
Shinya Yamanaka, MD, PhD the current ISSCR president, will remain in an executive role on the Board of Directors as the immediate past president. Fred H. Gage, PhD, who served this year as past president, will advise the board in an ex officio capacity.
The new leadership will be formerly introduced at the ISSCR 11th Annual Meeting in Boston, Massachusetts, USA. For more information on the terms of appointment, visit the elections webpage.
|4. 2013 Regional Forum Series
For 2013, the ISSCR is expanding the global reach of our educational programming with two events presented as a part of the 2013 Regional Forum Series. These Regional Forums are designed to complement the ISSCR Annual Meeting by offering a more focused look at specific topics within stem cell research presented in more intimate settings.
Florence, Italy is the home of the Renaissance and many marvels of architecture, engineering and science. Against this backdrop, the ISSCR is pleased to present Stem Cells in Translation, a program reflecting the major role of European research centers in the exciting transition of stem cell research to the clinic.
Registration and Abstract Submission for Stem Cells in Translation will open later this month. Learn more, view the preliminary program, hotel and travel information on the Forum website.
The ISSCR is pleased to return to Suzhou and again partner with Cold Spring Harbor Asia to present Stem Cells in Science and Medicine. The diverse program offers a wide range of stem cell topics including Stem Cells & Development, iPS and Reprogramming, Cancer Stem Cells and Therapy and more. View the complete list of sessions and confirmed speakers.
Registration and abstract submission for this meeting is now open through the Cold Spring Harbor Asia website. Please note that you must register for the meeting first if you wish to submit an abstract – you will be given a link and instructions for abstract submission in your registration confirmation email.
More information on this meeting including travel and hotel information is available on the Forum website.
|5. News Roundup
Italy. On March 21, 2013, the health minister of Italy announced that an experimental and unproven treatment using stem cells developed by the privately owned Stamina Foundation could be used to treat 32 terminally ill patients. Read more.
California, USA. The California Institute for Regenerative Medicine (CIRM) announced the winners of its Elevator Pitch Challenge on March 26, 2013. Read about the contest and view the winners and their videos.
|6. Job Opportunities
Seeking a job? Have a job opening? Visit the ISSCR’s Job Bank. ISSCR members receive a discount on job postings.
- FEATURED JOB POSTING Now you can feature your job opening both on the ISSCR Job Bank and in the ISSCR’s monthly e-newsletter, The Pulse. The e-newsletter is sent to more than 14,000 professionals in the stem cell field, so take advantage of this additional exposure!
|7. Funding and Awards
Alzheimer’s Research Trust, UK
This organization offers a range of funding opportunities in Alzheimer’s and related dementias that cover the full translational research pathway, including the basic disease process, early detection, identifying risk factors, alleviation and mechanisms of symptoms, and progress towards effective treatments. The following grant schemes are currently available:
- Equipment: provides between £10,000 - £100,000 for scientific equipment, flexibly defined. Due: April 26, 2013
- Network Cooperation: provides between £5,000 - £100,000 for projects that will promote cooperation and collaboration between two or more Alzheimer’s Research UK Network Centres. In addition to the Network Centres, the application can include co-applicants from elsewhere in the UK or abroad. Due: April 26, 2013
- Preparatory Clinical Research Fellowship: provides salary and research/travel costs (up to £10,000) for one year. Due: April 26, 2013
Biotechnology and Biological Sciences Research Council (BBSRC)
Next responsive mode application deadline: April 24, 2013.
California Institute for Regenerative Medicine (CIRM)
View a list of current Requests for Applications.
European Molecular Biology Organisation (EMBO)
Short- (up to three months) and Long- (1-2 years) Term Fellowships are currently available.
Long-Term Fellowship – offered twice a year to individuals holding a PhD with less than three years of postdoctoral training. Next deadline: August 15, 2013
Short-Term Fellowship – offered on a year-round basis to pre-doctoral students and individuals holding a PhD with less than 10 years of postdoctoral training.
Wellcome Trust (UK)
The Wellcome Trust is a UK-based organization that funds research to improve human and animal health. The Wellcome Trust supports research conducted outside the UK where research develops international partnerships, or focuses on biomedical or clinical medicine in developing countries. See their list of funding opportunities. In addition, view a complete list of upcoming deadlines.
Sir Henry Wellcome Postdoctoral Fellowship: May 20, 2013
|8. Meetings and Courses
ISSCR 11th Annual Meeting
International Conference 2013
Co-sponsored by HSCI and ISSCR
June 12-15, 2013
Boston, MA, USA
Stem Cells in Translation
Regional Forum Series 2013
Sept. 15 - 18, 2013
Palazzo dei Congressi
Stem Cells in Science and Medicine
Regional Forum Series 2013
Co-produced by ISSCR and Cold Spring Harbor Asia
Oct. 14-18, 2013
Stem Cell Meetings
8th Annual Wisconsin Stem Cell Symposium - Cell-Based Therapy for Heart and Vascular Disease
April 10, 2013
BioPharmaceutical Technology Center
Madison/Fitchburg, WI USA
In association with: University of Wisconsin Workshop: Developing Cellular Therapies: From Nonclinical Safety To Clinical Evaluation (April 9).
Hotel Discount Deadline: March 10, 2013
Poster Presentation Submission Deadline: March 22, 2013
Israstem Conference & Exhibition
April 22 - 23, 2013
Kfar HaMacabbia Conference Center
Ramat Gan, Israel
Abstract Submission Deadline: February 21, 2013
7th International Meeting of the Stem Cell Network NRW
April 23 - 24, 2013
In association with: 5th Bioinformatics Stem Cells Satellite Workshop
Poster abstract submission deadline: March 15, 2013
Second ESH-EHA Scientific Workshop on Leukemic and Cancer Stem Cells: Malignant Cells and Their Microenvironment
April 25 - 27, 2013
Mandelieu (near Nice), France
Abstract submission deadline: Feb. 15, 2013
GTC 10th Stem Cell Summit
April 29 - 30, 2013
Boston, MA, USA
Discounted Registration Deadline: February 28, 2013
Abstract Submission Deadline: March 29, 2013
The Next Gen Stem Cell Conference
May 8 - 9, 2013
Saratoga National Golf Club
Saratoga Springs, NY, USA
Discounted Registration Deadline: March 10, 2013
Registration Closes: May 1, 2013
V. Else Kröner-Fresenius Symposium on Adult Stem Cells in Aging, Diseases, and Cancer
May 24 - 26, 2013
Abstract Submission Deadline: February 15, 2013
Registration Closes: March 15, 2013
The Clinical Science of Regenerative Neurology
May 30 - 31, 2013
Edinburgh, Scotland, UK
Discounted Registration Deadline: March 1, 2013
Poster Presentation Submission Deadline: April 1, 2013
New Avenues for Brain Repair: Programming and Reprogramming the Central Nervous System
June 10 - 11, 2013
Boston, MA USA
Abstract submission deadline: March 15, 2013
Discounted registration deadline: April 5, 2013
Poster abstract submission deadline: April 5, 2013
eCM XIV: Stem & Progenitor Cells for Musculoskeletal Regeneration
June 23 – 25, 2013
Abstract Submission Deadline: April 8, 2013
Discounted Registration Deadline: June 1, 2013
ISEH - 42nd Annual Scientific Meeting
Aug. 22 - 25, 2013
Abstract submission deadline: April 12, 2013
Discounted registration deadline: June 3, 2013
Stem Cell Courses
The 21st School in Life Sciences: Stem Cells and Regenerative Biology
July 21-25, 2013
The Hebrew University of Jerusalem
Application Deadline: May 31, 2013
EMBO Practical Course: Current methods in cell biology
Sept. 26 - Oct. 4, 2013
Stem Cells: A Pathway Through the Maze
Dec. 11 - 13, 2013
Oxford, United Kingdom
Application Deadline: December 9, 2013
Regularly Occurring Courses
Cellular Dynamics International (CDI): iCertification Courses
Madison, WI, USA
Two-day training courses for CDI's iCell Products.
Life Technologies: LifeLab Pluripotent Stem Cell Workshops
Various Locations, Global
Training in culturing and characterizing hESCs and iPSCs and reprogramming techniques offered at various locations throughout the year.
STEMCELL Technologies: Training Courses
Vancouver, BC, Canada
Ongoing series of a range of specialized stem cell courses.
|9. Literature Highlights
Stem Cell Reports. With the publishing of its inaugural issue in June 2013, the ISSCR’s new online, open-access journal has already received a significant number of manuscripts – is yours one of them? Stem Cell Reports focuses on shorter, single-point manuscripts that report original research with conceptual or practical advances of broad interest to stem cell biologists and clinicians. As an added benefit, ISSCR members will receive a 15% discount on the publication fee. Visit the Stem Cell Reports website to find out more or to submit your manuscript.
Ding, Q., Regan, S. N., Xia, Y., Oostrom, L. A., Cowan, C. A. and Musunuru, K. (2013). Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs. Cell Stem Cell 12, 393-394.
Kaneko, S. and Yamanaka, S. (2013). To be immunogenic, or not to be: that’s the iPSC question. Cell Stem Cell 12, 385-386.
Refers to Araki et al. (2013) and Guha et al. (2013).
Hanoun, M. and Frenette, P. S. (2013). This niche is a maze; an amazing niche. Cell Stem Cell 12, 391-392.
Refers to Ding and Morrison (2013) and Greenbaum et al. (2013).
Benayoun, L. and Shaked, Y. 2013. In vitro enrichment of tumor-initiating cells from human established cell lines. Curr Protoc Stem Cell Biol 24:3.7.1–3.7.15.
Morte, M. I., Carreira, B. P., Machado, V., Carmo, A., Nunes-Correia, I., Carvalho, C. M. and Araújo, I. M. 2013. Evaluation of proliferation of neural stem cells in vitro and in vivo. Curr Protoc Stem Cell Biol 24:2D.14.1–2D.14.24.
Stecca, B., Santini, R., Pandolfi, S. and Penachioni, J. Y. 2013. Culture and isolation of melanoma-initiating cells. Curr Protoc Stem Cell Biol 24:3.6.1–3.6.12.
Shyh-Chang, N. and Daley G. Q. (2013). Lin28: primal regulator of growth and metabolism in stem cells. Cell Stem Cell 12, 395-406.
Araki, R., Uda, M., Hoki, Y., Sunayama, M., Nakamura, M., Ando, S., Sugiura, M., Ideno, H., Shimada, A., Nifuji, A. and Abe, M. (2013). Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embyronic stem cells. Nature 494, 100-104.
Beerman, I., Bock, C., Garrison, B. S., Smith, Z. D., Gu, H., Meissner, A. and Rossi, D. J. (2013). Proliferation dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging. Cell Stem Cell 12, 413-425.
Ding, L. and Morrison, S. J. (2013). Haematopoetic stem cells and early lymphoid progentiors occupy distinct bone marrow niches. Nature 495, 231-235.
Filareto, A., Parker, S., Darabi, R., Borges, L., Iacovino, M., Schaaf, T., Mayerhofer, T., Chamberlain, J. S., Ervasti, J. M., McIvor, R. S., Kyba, M. and Perlingeiro, R. C. (2013). An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells. Nat Commun 4, 1549.
Gekas, C. and Graf, T. (2013). CD41 expression marks myeloid biased adult hematopoietic stem cells and increases with age. Blood doi:10.1182/blood-2012-09-457929.
Gracz, A. D., Fuller, M. K., Wang, F., Li, L., Stelzner, M., Dunn, J. C. Y., Martin, M. G. and Magness, S. T. (2013). CD24 and CD44 mark human intestinal epithelial cell populations with characteristics of active and facultative stem cells. Stem Cells doi:10.1002/stem.1391.
Greenbaum, A., Hsu, Y. M., Day, R. B., Schuettpelz, L. G., Christopher, M. J., Borgerding, J. N., Nagasawa, T. and Link, D. C. (2013). CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance. Nature 495, 227-230.
Guha, P., Morgan, J. W., Mostoslavsky, G., Rodrigues, N. P. and Boyd, A. S. (2013). Lack of immune response to differentiated cells derived from syngeneic induced pluripotent stem cells. Cell Stem Cell 12, 407-412.
Klauke, K., Radulović, V., Broekhuis, M., Weersing, E., Zwart, E., Olthof, S., Ritsema, M., Bruggeman, S., Wu, X., Helin, K., Bystrykh, L. and de Haan, G. (2013). Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation. Nat Cell Biol 15, 353-362.
Sirko, S., Behrendt, G., Johansson, P. A., Tripathi, P., Costa, M., Bek, S., Heinrich, C., Tiedt, S., Colak, D., Dichgans, M., Fischer, I. R., Plesnila, N., Staufenbiel, M., Haass, C., Snapyan, M., Saghatelyan, A., Tsai, L. H., Discher, A., Grobe, K., Dimou, L. and Götz, M. (2013). Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog glia. Cell Stem Cell 12, 426-439.
Takashima, S., Paul, M., Aghajanian, P., Younossi-Hartenstein, A. and Hartenstein, V. (2013). Migration of Drosophila intestinal stem cells across organ boundaries. Development 140, 1903-1911.
Tan, D. W. M., Jensen, K. B., Trotter, M. W. B., Connelly, J. T., Broad, S. and Watt, F. M. (2013). Singe-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells. Development 140, 1433-1444.
Tanaka, T., Komai, Y., Tukuyama, Y., Yanai, H., Ohe, S., Okazaki, K. and Ueno, H. (2013). Identification of stem cells that maintain and regenerate lingual keratinized epithelial cells. Nat Cell Biol doi:10.1038/ncb2719.