This issue is sponsored by:


1. Editor's Message

Carl Wonders, PhD

Final days to submit your abstract! The Abstract Submission Deadline is now February 14 at 5:00 p.m. US Central Time. Read more about Abstract Submission, associated Travel and Poster Awards, registration and other information about the ISSCR 11th Annual Meeting in Section 2.

ISSCR Connect. On February 19 at 1 PM ET (USA), Dr. Song Li, bioengineer at the University of California, Berkeley, will present his latest research on stem cells in cardiovascular disease and regeneration. See Section 3 for more details.

The ISSCR's new journal – Stem Cell Reports. Our new open-access journal, Stem Cell Reports is now accepting manuscripts. Under the editorship of Professor Christine Mummery, PhD, Leiden University Medical Center, Stem Cell Reports will publish its inaugural issue in June 2013. Learn more in Section 8.

2013 ISSCR Elections. The 2013 elections for the ISSCR Board of Directors will open on February 20. Current active and associate members are invited to:

  1. Vote for a vice president
  2. Vote for a treasurer
  3. Vote for a new member of the ISSCR Board of Directors
  4. Endorse the re-appointment of three current directors
Members, look out for an email with ballot instructions. If you are not yet a member or have not renewed your membership for 2013, join now and take this opportunity to help shape the future directions of the ISSCR. Voting closes March 20. Find our more about the elections and meet the candidates.

Contact Glori Rosenson (grosenson@isscr.org; +1-224-592-5755) with questions.

ISSCR Regional Conferences. Join us in September and October for two regional conferences as part of the ISSCR 2013 Regional Conference Series. Visit the Conference Series website for more information.

Reach 14,000 – Sponsor The Pulse e-newsletter. Did you know each month an exclusive sponsorship with ad space is available for the ISSCR's e-newsletter, The Pulse? By sponsoring this month's e-newsletter, STEMCELL Technologies benefits from exposure to more than 14,000 stem cell researchers, clinicians, regulatory officials, industry representatives, government authorities and others with an interest in stem cell research. Contact Amy Claver to reserve space for select upcoming issues.

 

2. ISSCR 11th Annual Meeting

ISSCR 11th Annual Meeting
June 12-15, 2013
Boston, Massachusetts, USA

Co-sponsored by the Harvard Stem Cell Institute

Important Dates
Abstract Submission Deadline EXTENDED to February 14
Early Registration Deadline April 17
Housing Service Deadline May 15

Hurry! The last chance to submit abstracts is February 14 at 5:00 p.m. Central Time (USA). Present your latest research to the top names in the stem cell field. In addition to the three evening poster sessions, more than 75 concurrent oral presentations and 85 poster teasers will be selected from submitted abstracts. View the Annual Meeting Website for more information on how to submit an abstract, including the Call for Abstracts, Frequently Asked Questions and Author Guidelines.

Be sure to apply for Travel and Poster Awards when submitting your abstract!

The Early Registration Deadline is April 17. Take advantage of reduced rates by registering today. Current ISSCR members receive an even greater discount on the registration fees; if you are not yet a member, you can join concurrently with your registration for the meeting and still receive the discount. Contact Rico Blanco (rblanco@isscr.org; +1-224-592-5756) with questions.

Plan your trip to Boston. The Headquarters Hotel for the ISSCR 11th Annual Meeting will be the Westin Boston Waterfront. Rooms are available at discounted rates through the ISSCR Housing Service at this and other area hotels. Upon completion of your meeting registration online, you will be automatically taken to the Housing Service website. Alternatively, you can follow the link in your registration confirmation email. See our hotel and travel page for more information.

Pre-Meeting Events. Plan to arrive early and participate in these pre-meeting events happening the morning of Wednesday, June 12 from 8:30 a.m. to 12:30 p.m.

  • Industry Wednesday Symposia – These sessions, which are offered Wednesday morning before the opening plenary session, give companies the opportunity to present topical scientific issues in stem cell science as framed by industry leaders. ThermoFisher will be presenting at this year’s meeting, and other companies are expected to confirm soon. Contact Amy Claver aclaver@isscr.org or Drew Rich drich@isscr.org for more information about participating.
  • Ethics Focus Session – This year’s Ethics Focus Session aims to address the current challenges and future directions facing the donation of somatic cells for stem cell research purposes. The session will combine speaker presentations, panel discussions and question & answer sessions with the audience. Additional information on this session will be made available on the ISSCR 11th Annual Meeting website once it becomes available.

Interested in organizing a Focus Session? The ISSCR is now accepting applications for additional Focus Sessions to be held the morning prior to the start of the ISSCR 11th Annual Meeting. For more information or to apply, download the Application Package.

Junior Investigator-Specific Events. Junior investigators will have the opportunity to participate in specific networking and social events at the 2013 Annual Meeting in Boston.

  • Meet the Experts Lunches*: June 13 and 14, 11:30 a.m. – 1:00 p.m.
  • Career Panel Lunch and Discussion*: June 15, 11:30 a.m. – 1:00 p.m.

*Pre-registration for these events is required; information will be emailed to eligible registrants of the meeting.

Special Interest Group Meet-Ups. This year, the ISSCR is providing the opportunity to develop informal sessions for attendees to meet and discuss research topics of mutual interest. Find out more in Section 3.

Exhibitors
Find business solutions and meet one-on-one with industry leaders involved in the latest technology and services in the field of stem cell research and regenerative medicine in the exhibit hall. View the listing of exhibiting companies on the ISSCR Annual Meeting website.

The ISSCR thanks its generous supporters who make the many events and offerings at the Annual Meeting possible:

Co-sponsor:

Meeting Supporters:
 

The Albert Einstein College of Medicine
BioLamina
Boston Children’s Hospital/Stem Cell Program 
Ruth L. and David S. Gottesman Institute for Stem Cell Biology and Regenerative      Medicine
Lieber Institute for Brain Development
Massachusetts General Hospital/Center for Regenerative Medicine
The New York Stem Cell Foundation
StemCells, Inc.
University of Pittsburgh, McGowan Institute for Regenerative Medicine

Interested in becoming a supporter of the ISSCR 11th Annual Meeting? Contact Amy Claver, aclaver@isscr.org.

Help to spread the word! Download the ISSCR 11th Annual Meeting PowerPoint® slide for use in your next presentation.

Are you on Twitter? Follow us @ISSCR to stay up to date on the latest Annual Meeting and Society news. Use the hashtag #ISSCR2013 to follow and join in on the conversation all the way through the meeting.

3. ISSCR Connect

The ISSCR’s online education and networking platform, ISSCR Connect, is open to all ISSCR members. Make the most of the available presentations and take advantage of the networking features to search for and connect with colleagues. Not yet a member? Join today!

Tuesday, February 19, 2013, 1 p.m. ET (USA)
“Stem Cells: Vascular Diseases, Regeneration and Mechanobiology”

Song Li, Ph.D.
Professor, Department of Bioengineering
University of California, Berkeley

Stem cells play an important role in tissue remodeling. In his talk, Dr. Li will use blood vessels as an example to illustrate that stem cells participate in the development of vascular diseases and also are important for the generation of blood vessels.  Bioactive materials can be engineered to recruit endogenous stem cells from surrounding tissues and circulation for vascular regeneration. In addition, the biophysical properties of biomaterials can regulate stem cell differentiation and cell reprogramming.

Special Interest Group Meet-Ups at the ISSCR 11th Annual Meeting. If you are interested in developing an informal session at the Annual Meeting, take advantage of the discussion forums on ISSCR Connect to start the conversations and find other ISSCR members with mutual interests. For more information, contact Carl Wonders cwonders@isscr.org or +1-224-592-5723.

If you are an approved ISSCR member, you have access to ISSCR Connect. Check your email for your login and password information. Forgot your password?

Problems logging in? Email Carl Wonders for assistance. We recommend checking your login well in advance of the presentation to ensure that any issues are resolved in time, as presentations begin promptly at the listed times.

 

4. News Roundup

Australia. On January 14, Genea Stem Cells (GSC) announced the addition of 25 disease-specific embryonic pluripotent stem cell lines to the NIH registry. These cell lines carry specific mutations that give rise to various severe diseases, including several rare genetic disorders. Read more.

Scotland, UK. On February 5, a research team based in Scotland published a new technique for the three-dimensional “printing” of viable human embryonic stem cells. Read more or read the article by Faulkner-Jones et al.

New York, USA. On February 5, the Vilcek Foundation announced that Joanna Wysocka was named a winner of the 2013 Vilcek Prize for Creative Promise in Biomedical Science. Dr. Wysocka had previously been a recipient of the ISSCR-University of Pittsburgh Outstanding Young Investigator Award in 2010. Read more.

 

5. Job Opportunities
Seeking a job? Have a job opening? Visit the ISSCR’s Job Bank. Upgrade to a “Featured Job” and have your position highlighted here in The Pulse.

 

6. Funding and Awards

Biotechnology and Biological Sciences Research Council (BBSRC)
Next responsive mode application deadline: April 24, 2013.

California Institute for Regenerative Medicine (CIRM)
View a list of current Requests for Applications.

European Molecular Biology Organisation (EMBO)
Short- (up to three months) and Long- (1-2 years) Term Fellowships are currently available.
Long-Term Fellowship – offered twice a year to individuals holding a PhD with less than three years of postdoctoral training. Next deadline: February 15, 2013
Short-Term Fellowship
– offered on a year-round basis to pre-doctoral students and individuals holding a PhD with less than 10 years of postdoctoral training.

Wellcome Trust (UK)
The Wellcome Trust is a UK-based organization that funds research to improve human and animal health. The Wellcome Trust supports research conducted outside the UK where research develops international partnerships, or focuses on biomedical or clinical medicine in developing countries. See their list of funding opportunities.. In addition, view a complete list of upcoming deadlines.

  • New Investigator Awards: March 4, 2013
  • Early Postdoctoral Training Fellowship for Clinician Scientists: April 5, 2013
  • Sir Henry Wellcome Postdoctoral Fellowship: May 20, 2013

 

7. Meetings and Courses

Keystone Symposia: Stem Cells in Tissue Homeostasis and Disease
Feb. 24 - March 1, 2013
Banff, AB Canada

Biobanking 2013
Feb. 27, 2013
The Royal College of Pathologists, 2 Carlton House Terrace
London, United Kingdom

CiRA International Symposium 2013
March 11 - 12, 2013
Kyoto, Japan
Poster abstract submission deadline: Jan. 18, 2013

2013 Hilton Head Workshop: Regenerative Medicine - Technologies Enabling Novel Therapies
March 20 - 23, 2013
Hilton Head Island, SC USA
Discounted registration deadline: Feb. 18, 2013

StemCONN 2013: Realizing the Promise
April 3, 2013
New Haven, CT USA
Poster abstract submission deadline: Jan. 20, 2013
Discounted registration deadline: March 15, 2013
Registration closes: March 29, 2013

2nd Annual Cancer Immunotherapy Conference
April 4 - 5, 2013
Washington, DC USA

8th Annual Wisconsin Stem Cell Symposium - Cell-Based Therapy for Heart and Vascular Disease
April 10, 2013
BioPharmaceutical Technology Center
Madison/Fitchburg, WI USA
In association with: University of Wisconsin Workshop: Developing Cellular Therapies: From Nonclinical Safety To Clinical Evaluation (April 9).
Hotel Discount Deadline: March 10, 2013
Poster Presentation Submission Deadline: March 22, 2013

Israstem Conference & Exhibition
April 22 - 23, 2013
Kfar HaMacabbia Conference Center
Ramat Gan, Israel
Abstract Submission Deadline: February 21, 2013

7th International Meeting of the Stem Cell Network NRW
April 23 - 24, 2013
Cologne, Germany
In association with: 5th Bioinformatics Stem Cells Satellite Workshop
Poster abstract submission deadline: March 15, 2013

Second ESH-EHA Scientific Workshop on Leukemic and Cancer Stem Cells: Malignant Cells and Their Microenvironment
April 25 - 27, 2013
Mandelieu (near Nice), France
Abstract submission deadline: Feb. 15, 2013

GTC 10th Stem Cell Summit
April 29 - 30, 2013
Boston, MA, USA
Discounted Registration Deadline: February 28, 2013
Abstract Submission Deadline: March 29, 2013

The Next Gen Stem Cell Conference
May 8 - 9, 2013
Saratoga National Golf Club
Saratoga Springs, NY, USA
Discounted Registration Deadline: March 10, 2013
Registration Closes: May 1, 2013

V. Else Kröner-Fresenius Symposium on Adult Stem Cells in Aging, Diseases, and Cancer
May 24 - 26, 2013
Wartburg Hotel
Eisenach, Germany
Abstract Submission Deadline: February 15, 2013
Registration Closes: March 15, 2013

The Clinical Science of Regenerative Neurology
May 30 - 31, 2013
Edinburgh, Scotland, UK
Discounted Registration Deadline: March 1, 2013
Poster Presentation Submission Deadline: April 1, 2013

New Avenues for Brain Repair: Programming and Reprogramming the Central Nervous System
June 10 - 11, 2013
Boston, MA USA
Abstract submission deadline: March 15, 2013
Discounted registration deadline: April 5, 2013
Poster abstract submission deadline: April 5, 2013

ISSCR 11th Annual Meeting
Co-Sponsored by HSCI and ISSCR
June 12 - 15, 2013
Boston, MA USA
Abstract submission deadline: February 7, 2013
Discounted registration deadline: April 17, 2013

ISSCR 2013 Conference Series
Stem Cells In Translation

September 15-18, 2013
Firenzefiera, Florence, Italy

Stem Cells in Science and Medicine
Co-organized by ISSCR and Cold Spring Harbor Asia
October 14-17, 2013
Suzhou, China

Courses

EMBL Advanced Course: Development of Transgenic Animal Models Using Zinc Finger Nucleases
Feb. 25 - 27, 2013
Heidelberg, Germany
 

EMBO Practical Course: High-Throughput RNAi and Data Analysis
March 3 - 8, 2013
Heidelberg, Germany

The 21st School in Life Sciences: Stem Cells and Regenerative Biology
July 21-25, 2013
The Hebrew University of Jerusalem
Jerusalem, Israel
Application Deadline: May 31, 2013

View the complete list of meetings or stem cell courses.

 

8. Literature Highlights

Call for Papers – Stem Cell Reports. With the inaugural issue in June 2013, the ISSCR’s new online, open-access journal is accepting manuscript submissions. Stem Cell Reports focuses on shorter, single-point manuscripts that report original research with conceptual or practical advances of broad interest to stem cell biologists and clinicians. As an added benefit, ISSCR members will receive a 15% discount on the publication fee. Visit the Stem Cell Reports website to find out more or to submit your manuscript.

Cell Research – Special Issue on Stem Cell Biology. The January 2013 issue of Cell Research features articles and reviews covering the breadth of stem cell research including cell biology, regenerative medicine and disease applications. All issues are currently freely available. View the online table of contents.

Previews

Bowman, T. V. and Zon, L. I. (2013). Ageing: stem cells on a stress-busting diet. Nature doi: 10.1038.nature11948.

Refers to Warr et al. (2013)

Wu, M. V. and Hen, R. (2013). The young and the restless: regulation of adult neurogenesis by Wnt signaling. Cell Stem Cell 12, 139-140

Refers to Jang et al. (2013) and Sieb et al. (2013)

Reviews

Blanpain, C. (2013). Tracing the cellular origin of cancer. Nat Cell Biol 15, 126-134.

Signer, R. A. J. and Morrison, S. J. (2013). Mechanisms that regulate stem cell aging and life span. Cell Stem Cell 12, 152-165.

Smith, Z. D. and Meissner, A. (2013). DNA methylation: roles in mammalian development. Nat Rev Genet doi:10.1038/nrg3354.

Research Articles

Ben-David, U., Gan, Q. F., Golan-Lev, T., Arora, P., Yanuka, O., Oren, Y. S., Leikin-Frenkel, A., Graf, M., Garippa, M., Boehringer, M., Gromo, G. and Benvenisty, N. (2013). Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen. Cell Stem Cell 12, 167-179.

Chang, C. Y., Pasolli, H. A., Giannopoulou, E. G., Guasch, G., Gronostajski, R. M., Elemento, O. and Fuchs, E. (2013). NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche. Nature doi:10.1038/nature11847

Faulkner-Jones, A., Greenhough, S., King, J. A., Gardner, J., Courtney, A. and Shu, W. (2013). Development of a valve-based cell printer for the formation of human embryonic stem cell spheroid aggregates. Biofabrication 5, 015013.

Guha, P., Morgan, J. W., Mostoslavsky, G., Rodrigues, N. P. and Boyd, A. S. (2013). Lack of immune response to differentiated cells derived from syngeneic induced pluripotent stem cells. Cell Stem Cell doi: 10.1016/j.stem.2013.01.006

Jang, M. H., Bonaguidi, M. A., Kitabatake, Y., Sun, J., Song, J., Kang, E., Jun, H., Zhong, C., Su, Y., Guo, J. U., Wang, M. X., Sailor, K. A., Kim, J. Y., Gao, Y., Christian, K. M., Ming, G. L. and Song, H. (2013). Secreted Frizzled-Related Protein 3 regulates activity-dependent adult hippocampal neurogenesis. Cell Stem Cell 12, 215-223.

Leung, A., Ciau-Uitz, A., Pinheiro, P., Monteiro, R., Zuo, J., Vyas, P., Patient, R. and Porcher, C. (2013). Uncoupling VEGFA functions in arteriogenesis and hematopoietic stem cell specification. Dev Cell 24, 144-158.

Pang, W. W., Pluvinage, J. V., Price, E. A., Sridhar, K., Arber, D. A., Greenberg, P. L., Schrier, S. L., Park, C. Y. and Weissman, I. L. (2013). Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes. Proc Natl Acad Sci USA doi: 10.1073/pnas.1222861110.

Seib, D. R. M., Corsini, N. S., Ellwanger, K., Plaas, C., Mateos, A., Pitzer, C., Niehrs, C., Celikel, T. and Martin-Villalba, A. (2013). Loss of Dickkopf-1 restores neurogenesis in old age and counteracts cognitive decline. Cell Stem Cell 12, 204-214.

Warr, M. R., Binnewies, M., Flach, J., Reynaud, D., Garg, T., Malhotra, R., Debnath, J. and Passegué, E. (2013). FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature doi:10.1038/nature11895.

Yamji, M., Ueda, J., Hayashi, K., Ohta, H., Yabuta, Y., Kurimoto, K., Nakato, R., Yamada, Y., Shirahige, K. and Saitou, M. (2013). PRDM14 ensures naïve pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells. Cell Stem Cell doi: 10.1016/j.stem.2012.12.012

 


Informz for iMIS